CasNo.20380-11-4,C27H46O2 5,25R-Cholesten-3beta,26-diol 20380-11-4,(20380-11-4) Suppliers

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5,25R-Cholesten-3beta,26-diol 20380-11-4 C27H46O2

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Application:20380-11-4
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Details:

5,25R-Cholesten-3beta,26-diol Basic information

Product Name:	5,25R-Cholesten-3beta,26-diol
Synonyms:	(3S,8S,9S,10R,13R,14S,17R)-17-[(2R)-7-hydroxy-6-methyl-heptan-2-yl]-10,13-d;26-Hydroxycholesterol (not deuterated);26-Hydroxycholesterol-26,26,27,27,27-D5;(25R)-Cholest-5-en-3β,26β-diol;(25R)-Cholest-5-ene-3β,26-diol;27-OHC;5,25R-Cholesten-3beta,26-diol;cholest-(25R)-5-ene-3,27-diol
CAS:	20380-11-4
MF:	C27H46O2
MW:	402.65
EINECS:
Product Categories:	Hydroxycholesterol;Steroids & Hormones - 13C & 2H
Mol File:	20380-11-4.mol

5,25R-Cholesten-3beta,26-diol Chemical Properties

density

1.03

Safety Information

MSDS Information

5,25R-Cholesten-3beta,26-diol Usage And Synthesis

Definition

ChEBI: A 26-hydroxycholesterol in which the 25-position has R-configuration.

Uses

The liver x receptors (LXRα and LXRβ) are nuclear hormone receptors whose native ligands, oxysterols, induce the expression of genes involved in cholesterol and fatty acid metabolism. 27-hydroxy Cholesterol, a sterol 27-hydroxylase-mediated cholesterol hydroxylation product, activates LXRα and LXRβ in vitro with EC50 values of 85 and 71 nM, respectively, and is a potent suppressor of cholesterol biosynthesis. 25(R)-27-hydroxy Cholesterol is the more predominant-occurring (~80%) stereoisomer of the endogenous oxysterol 27-hydroxy cholesterol.[Cayman Chemical]

5,25R-Cholesten-3beta,26-diol Preparation Products And Raw materials