- Min.Order :1 Metric Ton
- Purity: 99.5%
- Payment Terms : L/C,T/T,
Keywords
D-Serine 312-84-5 C3H7NO3
Quick Details
- Appearance:Powder
- Application:312-84-5
- PackAge:Aluminium Foil Bag and Paper Drum
- ProductionCapacity:100|Metric Ton|Day
- Storage:1MT
- Transportation:By Sea/Air/DHL
Superiority:
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1.Noble Metal Catalysts (Pt.Pd...)
2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...)
3.OLED intermediates (Fluorene,Carbazole,Boric acid...)
4.Customs Synthesis
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Anyway ,if you need any chemicals from China ,Henan Tianfu can help you
Details:
| D-Serine Basic information |
| Product Name: | D-Serine |
| Synonyms: | (R)-2-AMINO-3-HYDROXYPROPIONIC ACID;β-Hydroxyalanine;D-SERINE 98.5%;D-Serine,>99%;D-2-Amino-3-Hydroxypropionic;(2R)-2-amino-3-hydroxy-propanoic acid;D-Serin;(R)-2-amino-3-hydroxypropanoic acid |
| CAS: | 312-84-5 |
| MF: | C3H7NO3 |
| MW: | 105.09 |
| EINECS: | 206-229-4 |
| Product Categories: | Amino Acid Derivatives;Serine [Ser, S];Amino Acids and Derivatives;alpha-Amino Acids;Amino Acids;Biochemistry;Amino Acids;Glutamate receptor;Glutamate;Amines;Inhibitors;Intermediates & Fine Chemicals;Neurochemicals;Pharmaceuticals;Pharmaceutical intermediates;D-Cycloserine intermediate;Lacosamide intermediate |
| Mol File: | 312-84-5.mol |
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| D-Serine Chemical Properties |
| Melting point | 220 °C |
| alpha | -14.75 º (c=10 2 N HCl) |
| storage temp. | Store at RT. |
| solubility | H2O: 0.1 g/mL, clear, colorless |
| form | Crystalline Powder |
| color | White |
| Water Solubility | 346 g/L (20 ºC) |
| Merck | 14,8460 |
| BRN | 1721403 |
| InChIKey | MTCFGRXMJLQNBG-UWTATZPHSA-N |
| CAS DataBase Reference | 312-84-5(CAS DataBase Reference) |
| EPA Substance Registry System | D-Serine(312-84-5) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 24/25-36-26 |
| WGK Germany | 3 |
| RTECS | VT8200000 |
| TSCA | Yes |
| HS Code | 29225000 |
| MSDS Information |
| Provider | Language |
|---|---|
| D-Serine | English |
| SigmaAldrich | English |
| ACROS | English |
| ALFA | English |
| D-Serine Usage And Synthesis |
| Description | D-serine is the D-form amino acid of the serine, its isomer L-form serine is the component of protein. D-serine is naturally found in the brain, and is a neuromodulator being capable of regulating the activities of neurons. It plays important physiological role in regulating mammalian brain function such as synaptic plasticity and memory. It is also related to the pathophysiology and therapy of several psychiatric and neurological conditions. It can be used for the treatment of cognitive decline, cocaine dependence and schizophrenia. It takes effect through acting as the co-agonist at NDMA receptors, being capable of enhancing the binding of glutamate and NMDA to NDMA receptors. |
| References |
# # Schell, M J, M. E. Molliver, and S. H. Snyder. "D-serine, an endogenous synaptic modulator: localization to astrocytes and glutamate-stimulated release. " Proceedings of the National Academy of Sciences of the United States of America 92.9(1995):3948-52. mothet, et al. "D-serine is an endogenous ligand for the glycine site of the NMDA receptor." Proceedings of the National Academy of Sciences 69A.5(2000):428–476. |
| Chemical Properties | White powder |
| Uses | A proteinogenic amino acids involved in the biosynthesis of purines and pyrimidines. Inhibitor of serine palmitoyltransferase. A neuromodulator. |
| Definition | ChEBI: The R-enantiomer of serine. |
| D-Serine Preparation Products And Raw materials |
| Raw materials | Chloroacetyl chloride-->2-N-BUTOXYETHYL METHACRYLATE-->DL-Serine-->AMINOACYLASE |
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