C15H20I4NNaO9 Levot...

C15H20I4NNaO9 Levothyroxine sodium 55-03-8

C15H20I4NNaO9 Levothyroxine sodium 55-03-8

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1 Metric Ton

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  • Min.Order :1 Metric Ton
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Keywords

Levothyroxine sodium 55-03-8 C15H20I4NNaO9

Quick Details

  • Appearance:Powder
  • Application:55-03-8
  • PackAge:Aluminium Foil Bag and Paper Drum
  • ProductionCapacity:100|Metric Ton|Day
  • Storage:1MT
  • Transportation:By Sea/Air/DHL

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Details:

 
Levothyroxine sodium Basic information
Product Name: Levothyroxine sodium
Synonyms: Levothyroxine sodium;Sodium 4-O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine;(S)-2-Amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propionic Acid odium;(S)-2-Amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propionic Acid Sodium Salt Sodium (S)-2-Amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propionate;sodiuM (S)-2-aMino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoate;L-Tyrosine,O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, sodiuM salt (1:1);Levothyroxine sodium ,T4;L-Thyroxine Sodium Salt Pentahydrate
CAS: 55-03-8
MF: C15H20I4NNaO9
MW: 888.93
EINECS: 200-221-4
Product Categories: Medicine intermediate;Amino Acids;Biochemistry;Biological-modified Amino Acids;Amino Acids & Derivatives;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Steroid and Hormone
Mol File: 55-03-8.mol
Levothyroxine sodium Structure
 
Levothyroxine sodium Chemical Properties
Melting point  207-210 (dec.)(lit.)
alpha  D20 -4.4° (c = 3 in 70% ethanol)
density  d420 2.381
storage temp.  2-8°C
solubility  cell culture medium: 0.1 mg/mL
form  powder
EPA Substance Registry System L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)- 3,5-diiodo-, monosodium salt(55-03-8)
 
Safety Information
Safety Statements  22-24/25
RIDADR  2811
WGK Germany  3
RTECS  YP2833760
F  3-8-10
HazardClass  6.1(a)
PackingGroup  II
MSDS Information
Provider Language
ACROS English
SigmaAldrich English
 
Levothyroxine sodium Usage And Synthesis
Chemical Properties White Solid
Uses One of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia.
Definition ChEBI: The sodium salt of L-thyoxine. It is used as replacement therapy in the treatment of hypothyroidism.
 
Levothyroxine sodium Preparation Products And Raw materials
Raw materials Acetic acid glacial-->L-Thyroxine-->Sodium levothyroxine

 

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