Triacetin 102-76-1 C9H14O6
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Triacetin Basic information |
Product Name: | Triacetin |
Synonyms: | 1,2,3-propanedioltriacetate;1,2,3-propanedioltriethanoate;2-(Acetyloxy)-1-[(acetyloxy)methyl]ethyl acetate;Acetin, tri-;Enzactin;femanumber2007;Fungacetin;Glycerol triacetate tributyrin |
CAS: | 102-76-1 |
MF: | C9H14O6 |
MW: | 218.2 |
EINECS: | 203-051-9 |
Product Categories: | Functional Materials;Plasticizer;Polyalcohol Ethers, Esters (Plasticizer);Biochemicals and Reagents;Building Blocks;C8 to C9;Carbonyl Compounds;Chemical Synthesis;Esters;Glycerolipids;Lipids;Organic Building Blocks;Triacylglycerols;Pharmaceutical intermediates;API intermediate;emulsifier;food additive |
Mol File: | 102-76-1.mol |
Triacetin Chemical Properties |
Melting point | 3 °C(lit.) |
Boiling point | 258-260 °C(lit.) |
density | 1.16 g/mL at 25 °C(lit.) |
vapor density | 7.52 (vs air) |
refractive index |
n |
FEMA | 2007 | (TRI-)ACETIN |
Fp | 300 °F |
form | Liquid |
color | Clear colorless |
explosive limit | 1.05%, 189°F |
Water Solubility | 64.0 g/L (20 ºC) |
Merck | 14,9589 |
Stability: | Stable. Incompatible with strong oxidizing agents. Combustible. |
CAS DataBase Reference | 102-76-1(CAS DataBase Reference) |
NIST Chemistry Reference | 1,2,3-Propanetriol, triacetate(102-76-1) |
EPA Substance Registry System | 1,2,3-Propanetriol, triacetate(102-76-1) |
Safety Information |
Safety Statements | 23-24/25 |
WGK Germany | 1 |
RTECS | AK3675000 |
TSCA | Yes |
HS Code | 29153930 |
Hazardous Substances Data | 102-76-1(Hazardous Substances Data) |
MSDS Information |
Provider | Language |
---|---|
1,2,3-Triacetoxypropane | English |
ACROS | English |
SigmaAldrich | English |
ALFA | English |
Triacetin Usage And Synthesis |
Chemical properties | Colorless, odorless oily liquid. It is miscible with ethanol, ether, benzene, chloroform and other organic solvents, soluble in acetone, insoluble in mineral oil. Slightly soluble in water. 25 ° C in water solubility of 5.9g / 100ml. |
Uses |
|
Production | It can be derived from the esterification of glycerol and acetic acid. After preheating glycerol to 50-60 ° C, add acetic acid, benzene and sulfuric acid. Heat and stir for refluxing dehydration, and recycle the benzene. Then add acetic anhydride for heating of 4h. After cooling, the mixture was neutralized with 5% sodium carbonate to pH 7, and the crude layer was dried and the crude oil was dried with calcium chloride. Distill under reduced pressure, collect the 128-131 ° C (0.93 kPa) fraction, namely glycerol triacetate. |
Content analysis | Accurately weigh about 1g of the sample, put it into a suitable pressure bottle, add 25 mL of 1mol / L. potassium hydroxide solution and 15 mL of isopropyl alcohol, add stopper, wrap with cloth and put it in a canvas bag. Put it into the water bath of 98 ℃ ± 2 ℃ for 1h, and the water level in the water bath should be slightly higher than the bottle level. Take the bottle out from the bag, cool it to room temperature in the air, unfold the cloth and stopper to release the residual pressure in the bottle, and then remove the cloth. Add 6 to 8 drops of phenolphthalein test solution (TS-167), apply 0.5mol / L sulfuric acid for titration of excess alkali until the pink could just disappeared. At the same time, perform a blank test. Each mL of 0.5mol / L sulfuric acid is equivalent to 36.37 mg of glyceryl triacetate (C9H14O6). |
Toxicity |
ADI is not subject to special provisions (FAO / WHO, 2001). GR.AS (FDA, § 182.1901, 2000). LD50 3000mg / kg (rat, oral). |
Chemical Properties | colourless liquid with a bitter taste |
Definition | ChEBI: A triglyceride obtained by acetylation of the three hydroxy groups of glycerol. It has fungistatic properties (based on release of acetic acid) and has been used in the topical treatment of minor dermatophyte infections. |
Uses | As fixative in perfumery; solvent in manufacture of celluloid, photographic films. Technical triacetin (a mixture of mono-, di-, and small quantities of triacetin) as a solvent for basic dyes, particularly indulines, and tannin in dyeing. |
Triacetin Preparation Products And Raw materials |
Preparation Products | ACETYLATEDMONO-GLYCERIDES |
Raw materials | Ethyl acetate-->Acetic acid glacial-->Glycerol-->Dehydrolyzing agent-->Amyl acetate |
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