717906-29-1 PF-431396 PF431396
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CAS No.:717906-29-1
LAL ID:xqy-170101
Chemical Names: PF-431396
Molecular Formula: C22H21F3N6O3S
Molecular Weight: 506.504 g/mol
Purity: 98%
Description
Dual focal adhesion kinase (FAK or PTK2) and proline-rich tyrosine kinase 2 (PYK2) inhibitor, with high affinity IC50 values of 1.5 nM and 11 nM for FAK and PYK2 respectively; PF 431396 increases bone formation and protects against bone loss in ovariectomized rats.
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