MK 571 115104-28-4 VERLUKAST
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CAS No.:115104-28-4
LAL ID:xqy-170111
Chemical Names: MK 571; VERLUKAST
Molecular Formula: C26H27ClN2O3S2
Molecular Weight: 515.083 g/mol
Purity: 98%
MK-571 is a selective, orally active CysLT1 receptor antagonist. It blocks the binding of LTD4, but not LTC4, to human and guinea pig lung membranes with Ki values of 0.22 nM and 2.1 nM, respectively. MK-571 attenuates kidney ischemia and reperfusion-induced airway hypersensitivity in rats. MK-571 alters bronchoalveolar lavage fluid proteome in a mouse asthma model.
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