Quick Details:
Product Name:Avanafil
Synonyms:(S)-2-(2-Hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylamino)-5-[(2-pyrimidinylmethyl)carbamoyl]pyrimidine;4-[(3-Chloro-4-methoxybenzyl)amino]-2-[2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide;4-[[(3-Chloro-4-Methoxyphenyl)Methyl] aMino]-2-[(2S)-2-(hydroxyMethyl)-1-pyrrolidinyl]-N-(2-pyriMidinylMethyl)-5-pyriMidinecarboxaMide
CAS:330784-47-9
MF: C23H26ClN7O3
MW:483.95
Chemical Properties:White or off-white crystalline power
MP:150-152°C
Usage:Avanafil is a highly selective PDE5 inhibitor with IC50 of 1 nM.
Packing:As required
What is avanafil
Avanafil relaxes muscles of the blood vessels and increases blood flow to particular areas of the body.
Avanafil is used to treat erectile dysfunction (impotence).
Avanafil may also be used for purposes not listed in this medication guide.
Applicaiton of Avanafil:
Avanafil comes as a tablet to take by mouth. It is usually taken with or without food as needed, about 30 minutes before sexual activity. Do not take avanafil more often than once in 24 hours. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take avanafil exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
COA of Avanafil:
| Items | Specifications | Results |
| Appearance | White or off-white crystalline power | Conforms |
| Identification | IR | Conforms |
| Solubility | Practically insoluble in water and Slightly soluble in ethanol | Conforms |
| Melting point | 162-165°C | Conforms |
| Heavy metals | ≤10ppm | 2ppm |
| Loss on drying | ≤0.5% | 0.13% |
| Sulphated ash | ≤0.1% | 0.08% |
| Purity(HPLC) | ≥98% | 99.32% |
| Any other impurities | ≤0.5% | 0.26% |
| Total impurities | ≤2% | 0.55% |
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