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CAS 57808-66-9 API Raw Material Drug Domperidone Reducing Nausea And Anti - Emetic
Quick detail
Domperidone | ||||
Synonyms: | 2h-benzimidazol-2-one,1,3-dihydro-5-chloro-1-(1-(3-(2,3-dihydro-2-oxo-1h-benzi;5-chloro-1-(1-(3-(2-oxo-1-benzimidazolinyl)propyl)-4-piperidyl)-2-benzimidaz;kw-5338;midazol-1-yl)propyl)-4-piperidinyl)-;DOMPERIDONE;4-(5-chloro-2-oxo-1-benzimidazolinyl)-1-[3-(2-oxobenzimidazolinyl)propyl]piperidine;ALPHA-[2-(DIISOPROPYLAMINO)ETHYL]-ALPHA-PHENYL-2-PYRIDINE-ACETAMIDE;5-CHLORO-1-[1-[3-(2,3-DIHYDRO-2-OXO-1H-BENZIMIDAZOL-1-YL)PROPYL]-4-PIPERIDINYL]-1,3-DIHYDRO-2H-BENZ-IMIDAZOL-2-ONE | |||
CAS: | 57808-66-9 | |||
MF: | C22H24ClN5O2 | |||
MW: | 425.91 | |||
EINECS: | 260-968-7 | |||
Product Categories: | Dopamine receptor;Aromatics;Heterocycles;Intermediates & Fine Chemicals; Pharmaceuticals; Isotope Labelled Compounds;VIOXX;Other APIs | |||
Melting point | 240-244°C | |||
storage temp. | Store at RT | |||
solubility | DMSO: >10 mg/mL | |||
form | solid | |||
color | white | |||
Stability: | Stable. Incompatible with strong oxidizing agents. |
Domperidone Description
Domperidone can be useful for treating nausea and vomiting due to many causes, including anti-cancer chemotherapy, general anaesthetics and in migraine. It can also used to prevent nausea and vomiting that may be caused by medicines for Parkinson's disease, such as levodopa, pramipexole and apomorphine.
Domperidone Indications
1 | 1, Digestion dysfunction symptoms caused by delayed gastric emptying, gastroesophageal reflux, chronic gastritis and esophagitis including nausea, vomiting, belching, abdominal fullness, abdominal pain, regurgitation caused burning sensation of mouth and stomach. |
2 | 2, Parkinson's disease and nausea and vomiting caused by various kinds of reasons such as functional, infection, dietary, radiotherapy or drug therapy and dopamine receptor agonists (such as levodopa, bromocriptine) therapy. |
3 | 3, it is suitable for treating migraine, dysmenorrhea, traumatic brain injury and intracranial lesions, radiation therapy and the nausea and vomiting caused by levodopa, nonsteroidal anti-inflammatory drug. |
4 | 4, it is effective in treating the nausea and vomiting caused by various organic or functional gastrointestinal disorders in elderly people. |
5 | 5, Domperidone is not effective in treating the vomiting caused by surgery or anesthesia and chemotherapy. |
Do not take domperidone if you
Important information about Domperidone
Motilium should be used with caution in
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