Quick Detail:
Product Name: Lapatinib ditosylate
Synonyms: Lapatinib ditosylate;benzenesulfonic acid: N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6 -[5-[(2-methylsulfonylethylamino)methyl]-2-furyl]quinazolin-4-amine: h ydrate;N-(3-Chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine bis(4-methylbenzenesulfonate);Lapatinib Ditosilate;Lapatinib, Tykerb, GW572016;Lapatinib Ditosylate (GW-572016);lapatinib(GW572016);Lapatinib ditosylate hydrate
CAS: 388082-78-8
MF: C41H40ClFN4O11S3
MW: 925.46
Product Categories: anti-neoplastic;Lapatinib;Anti-cancer&immunity;Inhibitors
Mol File: 388082-78-8.mol
COA:
TEST ITEMS | SPECIFICATION | RESULTS |
Description | Light yellow or almost white crystalline powder | Light Yellow powder |
Identification | IR | Positive |
Assay | 97.0~103.0% | 99.37% |
Melting Point | 70~80°C | 70.5~76.5°C |
Specific Rotation | +22~+26° | +23.09° |
Loss On Drying | 0.5%max | 0.25% |
Residue On Ignition | 0.1%max | 0.05% |
Heavy Metals | 20PPm max | <20PPm |
Organic Volatile Impurities | Meets the requirement. | Conforms |
Related Substances |
Single Impurity: 1.0%max | <1.0% |
Total Impurities: 2.0%max | <2.0% | |
Conclusion | The specification conforms to enterprise standard. |