Tretinoin Retin-A Topical Acne Treatment Medicine Raw Material Powder CAS 302-79-4

 

Quick detail

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Name: Tretinoin
CAS No.: 302-79-4
Formula: C20H28O2
Molecular Weight: 300.44
Synonyms: (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraenoate;all-trans-beta-Retinoic acid;Vitamin A acid;Tretinoine (French) (EINECS); Retin A;trans-Retinoic acid;all-trans-Vitamin A1 acid; AGN 100335; Vitamin A acid sodium salt;Vitamin A1 acid, all-trans-; Tretinoin USP26;
EINECS: 206-129-0
Density: 1.011 g/cm3
Melting Point: 179-184 °C
Boiling Point: 462.8 °C at 760 mmHg
Flash Point: 350.6 °C
Solubility: insoluble in water
Appearance: yellow-orange powder

package : 25KG/DRUM,5KG/TIN
Appearance: light yellow or orange crystal powder d A acid

 

Tretinoin? Descriptions

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1. Tretinoin (brand names Retin-A, Avita, Renova) is a derivative of vitamin A and is the treatment of choice for comedonal acne as well as whiteheads and blackheads.
2. It works by increasing skin cell turnover which promotes the extrusion of the plugged material in the follicle.
3. It also prevents the formation of new comedones.
4. Tretinoin is also the only topical medication that has been proven to improve the appearance of wrinkles.

 

Tretinoin? Usage

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1. Used for usual acne, lichen planus, white spot, hair red pityriasis and facial pityriasis simplex

2. Also can be used as an auxiliary therapy for psoriasis.
3. Can also be used in the treatment of multiple verruca vulgaris, and abnormal keratinization of various skin.
diseases such as ichthyosis, hair follicle keratinization disorder.
4. For cancer prevention and treatment of precancerous lesions, Such as white spot of the oral mucosa, laryngeal papilloma, stunting disease.
5. Used for skin malignant tumor such as squamous cell carcinomas and basal cell carcinoma, mycosis enzyme disease.
6. For acute early young granulocyte leukemia.

 

 

How Retin-A Works

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The effect of increased skin cell turnover can be irritation and flaking.

For this reason, many people stop using Retin-A after a couple of days to weeks, then think that it didn't work.

It is important to realize that Retin-A is very effective for whiteheads and blackheads, but it may take 6-9 weeks to see a noticeable difference.

It takes at least 6 months to see a noticeable difference in wrinkles.

The best benefit is seen if Retin-A is used for at least a year.

 

How to Use Retin-A

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Here are some guidelines for using Retin-A that may make sure you experience its full benefit:

1. Apply Retin-A in a thin layer at night. A small amount goes a long way.
2. In the morning, wash your face with a mild facial scrub or rough wash cloth. This will help reduce the noticeable flaking.
3. After washing, apply a good water-based moisturizer. Yes, guys, this applies to you too. The moisturizer will make the drying effect of the medicine more tolerable.
4. If flaking occurs during the day, use a washcloth to remove it and apply more moisturizer, or just apply moisturizer.
5. Try using a moisturizer that also contains a sunscreen. If not, apply sunscreen anytime you are in the sun even for a short amount of time. Tretinoin makes you more susceptible to sunburn.
6. When you first start using Retin-A, apply it every other night or every 3rd night. The flaking and irritation side effects are usually the worst in the first 2 weeks of application. As your skin adjusts to the medicine, you can apply it more frequently.
7. If you notice an increase in the irritation or flaking, it's okay to take a break for a couple of days. Just don't stop completely without consulting your health care provider!

 

Tretinoin? COA

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ITEM	SPECIFICATION
APPEARANCE	Yellow Crystalline Powder
IDENTIFIACATION	The IR absorption spectrum should correspond with reference spectrum
	Should exhibits maximum absorption at 352nm
LOSS ON DRYING	Not More Than 0.5%
RESIDUE ON IGNITION	Not More Than 0.1%
HEAVY METALS	Not More Than 0.002%
LIMIT OF ISOTRETINOIN	Not More Than 5.0%
ASSAY	98%-102%(Calculated On The Dried Basis)
CONCLUSION	It complies with all the requirements of usp34