buy Felodipine(Hypertension treatment) manufactry

Details:

the Company  Information

Hefei Lifeon Pharmaceutical Co., Ltdwas founded in 2002.It is ajoint-stock pharmaceutical enterprise integrating the research, development, production and sales of drugs (chemical, traditional Chinese medicine and biological antibody). With 3 industrial enterprises, 1 pharmaceutical commercial enterprise and 1 pharmaceutical retail chain, there are more than 700 employees. Company has been awarded as the"high and new technology enterprise", "anhui innovative enterprise", "enterprise technology centers recognized by the province", "one of the China's most valuable enterprise of pharmaceutical industry", ", new small and medium-sized enterprises in anhui province", "drugs slow-release engineering technology center in anhui province", "" intellectual property rights exemplary enterprises in hefei; The company's industrial and commercial enterprises are "anhui medical quality award", "double excellent award" winner, anhui province A class tax enterprise, anhui province to abide by the contract credit unit; Has built anhui postdoctoral research station; It is the legal person unit of anhui pharmaceutical industry association and vice President of China chemical pharmaceutical industry association.

     A strong and experienced scientific leadership team with full synthetic and medicinal chemistry capabilities and process research & development experiences, scientist of Hefei Lifeon Pharmaceutial Co. Ltd. are dedicated to synthesizing complicated pharmaceutical intermediates; natural products (especially in Flavonoid) extraction, isolation, purification and hemi-synthesis. The company provides comprehensive development of processes for manufacturing drugs in increasing quantities – from lab to pilot plant to commercial quantities with development base, pilot workshops and GMP-quality chemical production base. The facilities of GMP-quality kilo-lab and pilot plant of our production base realize chemical reaction development of high pressure, high temperature, low temperature, water-proof, oxygen-proof and high vacuums. Hefei Lifeon Pharmaceutial Co. Ltd. API branch has developed and produced dozens of advanced intermediates and fine chemicals as active pharmaceutical intermediates.

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Welcome to our Shanghai CPHI in June 2018. Our booth number is: W3C28

the Product  Information

【Product name】Felodipine；
4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinecarboxylic acid ethyl methyl ester 
【CAS No.】72509-76-3
【Structural formula】

【Molecular Formula】C18H19Cl2NO4

【Molecular Weight】384.26

【Appearance】 light yellow to white crystalline powder

【Use】Hypertension treatment
 

What field apply to

for the treatment of high blood pressure is a selective calcium antagonists, inhibit the main flow of extracellular calcium arterial smooth muscle cells, and selective expansion of small arteries, veins, no such effect, not cause orthostatic hypotension; myocardial also. no significant inhibition. This product reduces renal vascular resistance, while not affect glomerular filtration rate and creatinine clearance rate, renal blood flow did not change even slightly increased, there natriuretic and diuretic effect. It can be used to increase output and cardiac index, significantly reducing afterload, while the systolic function, preload and heart rate had no significant effect.

Felodipine is used to treat high blood pressure and stable angina.

Felodipine is a member of the 1,4-dihydropyridine class of calcium channel blockers. It is a racemic mixture, and is insoluble in water but is soluble in dichloromethane and ethanol.

Felodipine is a calcium channel blocker. Felodipine has additionally been found to act as an antagonist of the mineralocorticoid receptor, or as an antimineralocorticoid.