global AZD-9291/fac...

global AZD-9291/factory Osimertinib mesylate/1421373-66-1 Good Supplier In China

global AZD-9291/factory Osimertinib mesylate/1421373-66-1 Good Supplier In China

Min.Order / FOB Price:Get Latest Price

25 Metric Ton

FOB Price: USD 1.0000

  • Min.Order :25 Metric Ton
  • Purity: 99%
  • Payment Terms : L/C,D/P,T/T,

Keywords

global AZD-9291 factory Osimertinib mesylate 1421373-66-1 Good Supplier In China

Quick Details

  • Appearance:white crystallized powder
  • Application: Osimertinib mesylate; AZD-9291
  • PackAge:25 kilogram card board barrels,lined with douclbe plastic bags
  • ProductionCapacity:20/30/40/50|Kilogram|Month
  • Storage:Dry and ventilated
  • Transportation:by sea or by airport

Superiority:

global AZD-9291/factory Osimertinib mesylate/1421373-66-1 Good Supplier In China

 

AZD-9291 (Mesylate) Basic information
Product Name: AZD-9291 (Mesylate)
Synonyms: AZD-9291 (Mesylate);N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-2-propenamide methanesulfonate (1:1);AZD-9291 mesylate N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-2-propenamide methanesulfonate (1:1);Osimertinib mesylate;Mereletinib mesylate;Osimertinib;N-[2-(2-dimethylaminoethylmethylamino)-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide mesylate salt;Osimertinib Mesylate(AZD9291)
CAS: 1421373-66-1
MF: C28H33N7O2.CH4O3S

 

Details:

global AZD-9291/factory Osimertinib mesylate/1421373-66-1 Good Supplier In China

Shanghai topchem Co., LTD and integrated high-tech enterprise composed with Production , R&D and trading , Specialized in Quinolones Api and intermediatesVeterinary drugs and suppply CMO serviece for suctomers.                                                                                      1.good service, high quality with competitive price.   2.fast and safe deliver0y. 3.we have clients throughhout the world 4.exported areas: eurpore, southeast asia the middle east, south america and some other countries and areas. 5. Have our own r&d group.

What is AZD9291?

Osimertinib (previously known as mereletinib or AZD9291) is a third-generation epidermal growth factor receptor tyrosine kinase inhibitor drug.

AZD9291 is a Kinase Inhibitor. The mechanism of action of osimertinib is as a Kinase Inhibitor, and Cytochrome P450 3A Inhibitor, and Cytochrome P450 3A4 Inducer, and Cytochrome P450 1A2 Inducer, and Breast Cancer Resistance Protein Inhibitor.

As this agent is selective towards mutant forms of EGFR, its toxicity profile may be reduced when compared to non-selective EGFR inhibitors which also inhibit wild-type EGFR.

Function of AZD9291

AZD9291 used in the therapy of selected forms of advanced non-small cell lung cancer (NSCLC). Osimertinib is associated with a moderate rate of serum aminotransferase elevations during therapy and rare instances of clinically apparent acute liver injury.

 

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