Trilostane CAS 13647-35-3 Anti Estrogen Steroids Treatment of Cushing's Syndrome

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Trilostane CAS 13647-35-3 Anti Estrogen Steroids Treatment of Cushing's Syndrome

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Trilostane Introduction

Trilostane is an enzyme inhibiting medication. Its principal use is in the treatment of canine Cushing’s disease. In some cases, trilostane may also be an appropriate treatment for horses, cats and other conditions.

Trilostane is an inhibitor of 3β-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome and primary hyperaldosteronism. These are both disorders where excess amounts of corticosteroid hormones are produced in the body. Corticosteroids are essential for the body to make use of carbohydrates, fats and proteins and for a normal response to stress.

Trilostane can also be useful in the treatment of breast cancer that has relapsed in women who have gone through menopause.

Trilostane Uses in dogs

It is also the first drug approved to treat both pituitary-and adrenal-dependent Cushing's in dogs.

Trilostane — Drug Interactions and Potential Side Effects

Potential side effects include vomiting, reduced appetite, weight loss, diarrhea and tiredness. Rare instances of death have been reported. As each patient reacts differently to trilostane, arriving at the appropriate dosage is crucial in preventing instances of overdose and achieving the best possible outcome.

Trilostane COA

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Trilostane CAS 13647-35-3 Anti Estrogen Steroids Treatment of Cushing's Syndrome