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100427-26-7 Lercanidipine API C36H41N3O6
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Oral Powder Lercanidipine API Lowering Hypertension Raw Material Drugs 100427-26-7
Quick detail
Name: Lercanidipine
CAS No.: 100427-26-7
Formula: C36H41N3O6
Molecular Weight: 611.73
Appearance & Physical State: White to light yellow solid
Density: 1.177 g/cm3
Melting Point: 118-120ºC
Boiling Point: 712.5ºC at 760 mmHg
Flash Point: 384.7ºC
Refractive Index: 1.579
Vapor Pressure: 3.77E-20mmHg at 25°C
Lercanidipine Description
Lercanidipine is a type of drug called a calcium channel blocker, which works to reduce blood pressure by relaxing the muscles around the blood vessels. If you or someone you know is taking lercanidipine and you’d like to know more about how it works, this is for you.
Lercanidipine Usage
Lercanidipine is prescribed by doctors to treat high blood pressure when other blood pressure lowering drugs do not work (well enough).
How To use Lercanidipine
Lercanidipine should be taken at a fixed time (preferably in the morning) and always at least 15 minutes before eating.
Note: grapefruit may enhance the effect of this medication. Therefore do not eat/drink grapefruit (juice) if you are being treated with this medication.
Take lercanidipine tablets by mouth.
Swallow the tablets whole with a drink of water. Do not take lercanidipine with grapefruit juice or with a high-fat meal. Take your doses at regular intervals. Do not take your medicine more often then directed. Do not stop taking except when advised by your prescriber.
Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.
Lercanidipine Dosage
Lercanidipine is available in tablets of 10 and 20 mg. The doctor will know which strength is right for you. The usual dosage for adults aged 18 and over is one tablet once a day. Always follow the advice of the doctor.
A missed dose may still be taken, unless it is almost time for the next dose.
An overdose may cause a very low blood pressure, a rapid heartbeat or cause unconsciousness.
Always warn a doctor in the event of an overdose.
Lercanidipine Side effects
You may get side effects from this medication. The most important side effects include:
dizziness (especially when you stand up too quickly), sleepiness, fatigue
headache
palpitations
The leaflet lists all (other) side effects. Talk to a doctor if the side effects become serious, or if symptoms occur that are not listed in the leaflet
When should you not use Lercanidipine (contra-indications)
This medication should not be used when you have:
Driving Ability
Lercanidipine may sometimes cause dizziness or drowsiness. Once your body is used to a lower blood pressure, these symptoms usually disappear. Then you should be able to participate in traffic again.
Alcohol
Alcohol increases the effect that Lercanidipine has on the blood vessels. This may increase, or worsen, dizziness. Keep this in mind if you want to drink alcoholic beverages.
Interaction with other medications
Medications may affect each other. Regarding Lercanidipine, the following combinations of drugs apply (see leaflet for a complete, specified list):
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