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94-09-7 Benzocaine Ethyl 4-aminobenzoate
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Effective Active Pharmaceutical Ingredients Benzocaine Base Topical CAS 94-09-7 Drug
Quick detail
Product Name: | Benzocaine | ||
Synonyms: | AETHOFORM;anesthesin;AKOS BBS-00003658;4-AMINOBENZOIC ACID ETHYL ESTER;LABOTEST-BB LTBB000527;H-4-ABZ-OET;ETHYL 4-AMINOBENZOATE;ETHYL P-AMINOBENZOATE | ||
CAS: | 94-09-7 | ||
MF: | C9H11NO2 | ||
MW: | 165.19 | ||
EINECS: | 202-303-5 | ||
Product Categories: | Aromatic Esters;C8 to C9;Carbonyl Compounds;Esters;Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Research Chemical;Pharmaceutical intermediate;API;Pharma materials;Intermediate of Tetracaine hydrochloride | ||
Melting point | 88-90 °C | ||
Boiling point | 172 °C (12.7517 mmHg) | ||
density | 1.17 | ||
Fp | 172°C/13mm |
Benzocaine Description:
Benzocaine is the ethyl ester of p-aminobenzoic acid (PABA). It can be prepared from PABA and ethanol by Fischer esterification or via the reduction of ethyl p-nitrobenzoate. Benzocaine is sparingly soluble in water; it is more soluble in dilute acids and very soluble in ethanol, chloroform and ethyl ether. With the CAS NO.94-09-7, it is a local anesthetic commonly used as a topical pain reliever or in cough drops.
Uses of Benzocaine
1. Benzocaine is a local anesthetic commonly used as a topical pain reliever. It is the active ingredient in many over-the-counter anesthetic ointments (e.g. products for oral ulcers of Anbesol by Wyeth, Kank+a by Blistex, Orabase B and Orajel by Del Pharmaceuticals, and Ultracare by Ultradent). It is also combined with antipyrine to form A/B Otic Drops, (Brand name Auralgan) to relieve earpain and remove cerumen.
2. Benzocaine is used as a key ingredient in numerous pharmecuticals:Phenazone, an anti-inflammatory;Some glycerol-based ear medications for use in removing excess wax as well as relieving ear conditions such as Otitis Media and swimmers ear; Some previous diet products such as Ayds; Some condoms designed to prevent premature ejaculation. Benzocaine acts to desensitize the penis, and theoretically allows an erection to be maintained
Usual Adult Dose for Pain
Benzocaine topical 20% gel: | Sunburn: Apply to affected area as needed up to 4 times a day. |
Benzocaine topical 20% spray: |
Sunburn, pain, insect bites, pruritus: Hold container approximately 6 to 12 inches from skin and spray on affected area(s) until wet as needed up to 4 times a day. When applying to facial area spray into palm of hand, then rub on face avoiding area around eyes. |
Benzocaine topical 20% cream: | Sunburn, pain, pruritus, insect bites, poison ivy: Apply to affected area as needed not more than 1 to 3 times a day. |
Please be cautious about it as the following
1. Do not breathe dust;
2. Avoid contact with skin and eyes;
3. Wear suitable gloves and eye/face protection;
4. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice;
5. Avoid contact with skin;
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