High Purity EP/USP Everolimus Powder CAS 159351-69-6 Immunology Anti-cancer
Everolimus is the 40-O-(2-hydroxyethyl) derivative of sirolimus and works similarly to sirolimus as an inhibitor of mammalian target of rapamycin
It is currently used as an immunosuppressant to prevent rejection of organ transplants and treatment of renal cell cancer and other tumours. Much research has also been conducted on everolimus and other mTOR inhibitors as targeted therapy for use in a number of cancers.
Inhibition of mTOR, the molecular target of Everolimus, extends the lifespan of model organisms including mice, and mTOR inhibition has been suggested as an anti-aging therapy.
Product Name: Everolimus
CAS RN.: 159351-69-6
EINECS: Add
Molecular Weight: 958.2244
Molecular Formula: C53H83NO14
Density: 1.18g/cm3
Boiling Point(ºC): 998.7°C at 760 mmHg
Flash Point(ºC): 557.8°C
refractive_index: 1.548
| Items | Specifications | Results |
| Appearance | White to whitish crystal powder | Conforms |
| Loss on drying | NMT 0.5% | 0.33% |
| Residue on ignition | NMT 0.1% | Conforms |
| Heavy metal | NMT 20ppm | Conforms |
| Assay (HPLC) | NLT 99.5% | 99.77% |
| Related substances | NMT 0.5% | 0.23% |
| Single impurity | NMT 0.1% | 0.07% |
