99% Latanoprost 130209-82-4 Prostaglandin Drugs

Min.Order / FOB Price:Get Latest Price

10 Gram	Negotiable

10 Gram

Negotiable

Min.Order :10 Gram
Purity: 99%
Payment Terms : T/T,,MoneyGram

Keywords

99%min Latanoprost Latanoprost Manufacturer For Treatment Of Glaucoma

Quick Details

Appearance:White Powder
Application: It Can Be Used As Pharmaceutical Intermediates
PackAge:100g/ bag, 2 kg/ bag, 25kg/ carton or as required
ProductionCapacity:10000|Metric Ton|Month
Storage:Store in sealed containers at cool & dry place. Protect from light, moisture and pest infestation.
Transportation:By DHL, TNT, FedEx, HKEMS, UPS, Etc

Superiority:

Advantages:

Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.

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Details:

Latanoprost Basic information

a prostaglandin F2a analogue Latanoprost ophthalmic solution Side effects Product description Molecular Structure Adverse reactions and side effects Chemical Properties Uses Production method

Product Name:	Latanoprost
Synonyms:	XALATAN;ISOPROPYL (5Z, 9A,11A,15R)-9,11,15-TRIHYDROXY-17-PHENYL-18,19,20-TRINOR-PROST-5Z-EN-1-OATE;LATANOPROST;17-PHENYL-13,14-DIHYDRO TRINOR PROSTAGLANDIN F2ALPHA ISOPROPYL ESTER;9ALPHA,11ALPHA,15R-TRIHYDROXY-17-PHENYL-18,19,20-TRINOR-PROST-5Z-EN-1-OIC ACID, ISOPROPYL ESTER;9ALPHA, 11ALPHA, 15S-TRIHYDROXY-17-PHENYL-18,19,20-TRINOR-PROS-5Z-EN-1-OIC ACID, ISOPROPYL ESTER;(1r-(1-alpha(z),2-beta(r*),3-alpha,5-alpha))--methylethyleste;7-(3,5-dihydroxy-2-(3-hydroxy-5-phenylpentyl)cyclopentyl)-5-heptenoicaci1
CAS:	130209-82-4
MF:	C26H40O5
MW:	432.59
EINECS:	1806241-263-5
Product Categories:	Active Pharmaceutical Ingredients;Prostaglandins;Prostaglandin;Aromatics;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Other APIs;Inhibitors;Key Products
Mol File:	130209-82-4.mol

Latanoprost Chemical Properties

alpha	D20 +31.57° (c = 0.91 in acetonitrile)
storage temp.	−20°C
solubility	DMSO: freely soluble
form	oil
color	pale yellow
Merck	14,5376
InChIKey	GGXICVAJURFBLW-RDSJPUOVSA-N
CAS DataBase Reference	130209-82-4(CAS DataBase Reference)

Safety Information

WGK Germany	3
RTECS	MJ9669550

Latanoprost Usage And Synthesis


Product description	Latanoprost is a novel anti-glaucoma drugs which is suitable for the treatment of primary open-angle glaucoma or the tropical treatment of patients of ocular hypertension which is difficult to be treated and tolerated. It also has excellent efficacy in treating pigment dispersion glaucoma, angle recession, chronic angle-closure glaucoma, uveitis and quiescent exfoliation syndrome but is invalid for treating of uveitis in its active stage. Latanoprost is a kind of prostaglandin F2α derivative and is a kind of selective F2α receptor agonist. It is a non-active substance but can quickly penetrate into the cornea. It can be hydrolyzed into active free acid in the cornea and the plasma. It can increase the outflow amount of aqueous chambers water through the corner keratin layer. It only needs a small dose has a significant effect in boosting the outflow amount of the aqueous chambers water. The drug liquid can penetrate into the eyeball eyelashes suprachoroidal with excellent intraocular pressure lowering effect. Glaucoma will also clear the clogged trabecular mesh of patients.

Adverse reactions and side effects	Topical administration can result in mild to moderate conjunctival or scleral hyperemia. Occasionally slight redness on eyes can be observed. During the treatment of the first 2-3 days, the eyes will have a slight foreign body sensation; a small number of patients may get rash.
Chemical Properties	It is a kind of colorless oil. [α] D20 + 31.57 ° (C = 0.91, acetonitrile).
Uses	It can be used for the treatment of glaucoma.

Chemical Properties	Light Yellow Thick Oil
Uses	Prostanoid receptor ligand
Uses	antifungal polyene macrolide that is active in the cell membrane soluble 5% Acetic acid
Uses	Prostaglandin analog, used to treat glaucoma and other degenerative diseases of the eye.
Definition	ChEBI: A prostaglandin Falpha that is the isopropyl ester prodrug of latanoprost free acid. Used in the treatment of open-angle glaucoma and ocular hypertension.
Uses	Latanoprost is the isopropyl ester of 17-phenyl-13,14-dihydro prostaglandin F2α (17-phenyl-13,14-dihydro PGF2α). It is a prodrug form of the free acid, which is a potent agonist of the FP receptor in the eye. Latanoprost reduces intraocular pressure in glaucoma patients with few side effects. The EC50 value of latanoprost (tested as the free acid) for FP receptors is 3.6 nM.

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