99%min Bendamustine...

99%min Bendamustine Hydrochloride 3543-75-7

99%min Bendamustine Hydrochloride 3543-75-7

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10 Gram

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  • Min.Order :10 Gram
  • Purity: 99%min
  • Payment Terms : T/T,

Keywords

99%min Bendamustine Hydrochloride Bendamustine Hydrochloride Manufacturer For Antitumor

Quick Details

  • Appearance:White Powder
  • Application:For Pharmaceutical Raw Materials
  • PackAge:100g/ bag, 2 kg/ bag, 25kg/ carton or as required
  • ProductionCapacity:1000|Metric Ton|Month
  • Storage:Dry and cool place
  • Transportation:By DHL, TNT, FedEx, HKEMS, UPS, Etc

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Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.


1. Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are allowed to sell.


2 . Delivery We have stock, so we can delivery quickly at the very day when receive the payment. Within 24 hours after receiving the payment Lead time 4 or 7 days.


3 . Discreet package Safelyand Professionally Disguised Package Guaranteed. For your safety and to insure delivery all products will be packed in a discreet way to prevent any suspicions, no steroids related name will appear on the parcels. high successful delivery rate

4 . Warm after-sale service Any of your question would be solved for the first as soon as possible.

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Bendamustine hydrochloride Basic information
Product description Indications The dose and medication Pharmacological effects Pharmacokinetics Contraindications Drug Interactions Adverse reactions and side effects
Product Name: Bendamustine hydrochloride
Synonyms: bendamustine hydrochloride;BENDAMUSTIN HYDROCHLORIDE;CYTOSTASAN;1-methyl-5-bis(2-chloroethyl)amino-2-benzimidazolinebutryric acid hydrochloride;4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid hydrochloride;1-methyl-5-bis(2-chloroethyl)amino-2-benzimidazolinebutryricacihydrochlor;gamma(1-methyl-5-bis(beta-chloraethyl)aminobenzimidazoyl-2)buttersaeurehydro;BENDAMUSTINE HCL
CAS: 3543-75-7
MF: C16H22Cl3N3O2
MW: 394.72
EINECS: 1592732-453-0
Product Categories: API intermediates;Intermediates & Fine Chemicals;Pharmaceuticals;API;Amines;Heterocycles;Ribomustin, Treanda, SDX-105
Mol File: 3543-75-7.mol
Bendamustine hydrochloride Structure
 
Bendamustine hydrochloride Chemical Properties
Melting point  149-151°C
storage temp.  Desiccate at RT
solubility  H2O: >30mg/mL
color  off-white
Merck  14,1034
InChIKey ZHSKUOZOLHMKEA-UHFFFAOYSA-N
CAS DataBase Reference 3543-75-7(CAS DataBase Reference)
 
Safety Information
Hazard Codes  T,Xn
Risk Statements  60-61-22-40
Safety Statements  36-37
RIDADR  UN 2811 6.1 / PGIII
RTECS  DE1590000
HazardClass  6.1
PackingGroup  III
HS Code  29339900
 
Bendamustine hydrochloride Usage And Synthesis
Product description Bendamustine hydrochloride was first successfully developed in the early 1860s by the Ozegowski and his colleagues in the “Microbiology Experiment Association (Jena in Germany)”. The original purpose of developing it is intended to make a kind of alkylated chloremethine (a non-effective alkylating agent) be connected to a purine and amino acids. Compared with the chlorambucil, the main advantage of the newly synthesized compound is its water solubility. It was then widely applied. However, it is not until the end of the Cold War before the drug had been applied in Europe to clinical studies in either a number of single medication or in combination with other drugs for treating various kinds of blood malignancies and non-Hodgkin's lymphoma, multiple myeloma, CLL and breast cancer and some other solid tumors. The efficacy is very impressive. The drug had significantly reduced the recurrence rate and death rate with small adverse reactions and good security. So far, the clinical protocols of both monotherapy and combination therapy of bendamustine hydrochloride has been designated as either first-or second-line treatment option for treating various kinds of hematological malignancies by Europe and America clinical guidelines. 
From 1971 to 1992, Bendamustine was sold by the Jena pharmaceutical companies in the trade name of “Cytostasan”. From 1993, the cell growth inhibitor entered into market with the trade name “Ribomustine” mediated by Ribosepharm Company.
In 2003, the bendamustine hydrochloride product developed by German Ribosepharm Company entered into market in Germany with the trade name "Ribomustin". 
In 2008, the Bendamustine hydrochloride injection product developed by the United States Cephalon Company entered into market in United States under the trade name “Treanda” which is used for the treatment of the relapsed and refractory B-cell non-Hodgkin’s lymphoma which is failed be to be treated rituximab monotherapy.

 

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