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28860-95-9 High purity S-(-)-Carbidopa S-(-)-Carbidopa factory price
Product Name: | S-(-)-Carbidopa |
Synonyms: | 4-dihydroxy-alpha-methyl-alpha-hydrazino-(s)-benzenepropanoicaci;4-dihydroxy-alpha-methyl-alpha-hydrazino-l-hydrocinnamicaci;alpha-methyldopahydrazine;-Hydrazino-3,4-dihydroxy-methylbenzenep-ropanicacid;-Hydrazino-3,4-dihydroxy-methylhy-drocinnamicacid;hydrazino-alpha-methyldopa;l-alpha-methyldopahydrazine;mk486 |
CAS: | 28860-95-9 |
MF: | C10H14N2O4 |
MW: | 226.23 |
EINECS: | 249-271-9 |
Product Categories: | L-Aromatic Amino Acid Decarboxylase;API;Lodosyn |
Mol File: | 28860-95-9.mol |
S-(-)-Carbidopa Chemical Properties |
Melting point | 203-205° (dec); mp 208° |
alpha | D -17.3° (methanol) |
storage temp. | −20°C |
form | powder |
CAS DataBase Reference | 28860-95-9(CAS DataBase Reference) |
Safety Information |
WGK Germany | 3 |
RTECS | MW5298000 |
MSDS Information |
Provider | Language |
---|---|
3-(3,4-Dihydroxyphenyl)-2-hydrazinyl-2-methyl-propanoic acid | English |
SigmaAldrich | English |
S-(-)-Carbidopa Usage And Synthesis |
Chemical Properties | White Solid |
Uses | (S)-(-)-Carbidopa is a peripheral decarboxylase inhibitor that is commonly used in combination with L-DOPA (D533751) for treatment of Parkinsonism. S(-)-Carbidopa ( has also been shown to prolong the elimination half-life of L-DOPA from blood plasma and skeletal muscle. |
Uses | in combinaison with levodopa as antiparkinsonian;inhibits aromatic-L-amino-acid decarboxylase (DOPA Decarboxylase or DDC) |
Definition | ChEBI: 3-(3,4-Dihydroxyphenyl)propanoic acid in which the hydrogens alpha- to the carboxyl group are substituted by hydrazinyl and methyl groups (S-configuration). Carbidopa is a dopa decarboxylase inhibitor, so prevents conversi n of levodopa to dopamine. It has no antiparkinson activity by itself, but is used (commonly as its hydrate) in the management of Parkinson's disease to reduce peripheral adverse effects of levodopa. |
Biological Activity | Peripheral decarboxylase inhibitor, used in combination with levodopa for treatment of Parkinsonism. |
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