Pharmaceutical Imtermediates Ambroxol CAS: 18683-91-5 White Powder

Pharmaceutical Imtermediates Ambroxol CAS: 18683-91-5 White Powder

Specification:

Product Name: Ambroxol
Synonyms: 4-((2-amino-3,5-dibromobenzyl)amino)-(e)-cyclohexano;5-dibromophenyl)methyl)amino)-4-(((2-amino-trans-cyclohexano;Cyclohexanol, 4-((2-amino-3,5-dibromobenzyl)amino)- (E)-;Cyclohexanol, 4-[[(2-amino-3,5-dibromophenyl)methyl]amino]-, trans-;n-(2-amino-3,4-dibromociclohexil)-trans-4-aminociclohexanol;n-(2-amino-3,4-dibromocyclohexyl)-trans-4-aminocyclohexanol;N-(trans-4-Hidroxiciclohexil)-(2-amino-3,5-dibromobencil)amina;N-(trans-4-Hydroxycyclohexyl)-(2-amino-3,5-dibromobenzyl)-amine
CAS: 18683-91-5
MF: C13H18Br2N2O
MW: 378.1
EINECS: 242-500-3
Product Categories: API
MP: 233-234 C
Storage temp: 2-8°C
Supply Ability: 5000kg/month
Delivery time: Within 24 hours after payment.
Payment methods: T/T, , Moneygram,
Appearance : White crystalline powders
Usage : Expectorant, good sticky phlegm dissolving and lubrication to respiratory function, can promote the pulmonary surfactant secretion, respiration and liquid secretion and ciliary movement. Treatment of acute and chronic respiratory diseases, bronchial secretion abnormalities, etc..

Description:

Ambroxol is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Mucobrox, Mucol, Lasolvan, Mucoangin, Surbronc, Ambolar, and Lysopain. The substance is a mucoactive drug with several properties including secretolytic and secretomotoric actions that restore the physiological clearance mechanisms of the respiratory tract, which play an important role in the body’s natural defence mechanisms. It stimulates synthesis and release of surfactant by type II pneumocytes. Surfactant acts as an anti-glue factor by reducing the adhesion of mucus to the bronchial wall, in improving its transport and in providing protection against infection and irritating agents.Ambroxol is often administered as an active ingredient in cough syrup.

How Ambroxol Works

Ambroxol is the active agent in Mucosolvan. It makes phlegm in the airways thinner and less sticky. It does this by increasing the body's natural production of surfactant. This contributes to a secretomotoric effect: it helps the cilia - tiny hairs that line the respiratory tract - to transport the phlegm out of the lungs. Here is a step-by-step description of how Ambroxol works:

1. Ambroxol is quickly metabolised by the body. It goes straight to work at the mucus-secreting cells, where it changes the mucus so it becomes less viscous. This thinner, more liquid mucus helps lift the heavy, sticky phlegm off the walls of the airways.

2. Ambroxol frees and activates the cilia. Thanks to the effect of the thinner mucus, the cilia are no longer clogged by the thick, sticky phlegm. They are free to move again and help to push the phlegm up and out of the respiratory tract. Furthermore, Ambroxol enhances the movement of the cilia so they transport phlegm out of the airways more quickly.

3. Ambroxol is not a cough suppressant. It does not interfere with the body's natural cough response. This is important, because coughing is still needed to eject the excess phlegm from the airways. Ambroxol makes it easier to get the phlegm moving again.

4. As the active ingredient in Mucosolvan, Ambroxol has offered proven safety and effectiveness for many years.