NewblueCHEM- Foretinib (GSK1363089)

Min.Order / FOB Price:Get Latest Price

1 Metric Ton	FOB Price: USD 20.0000

1 Metric Ton

FOB Price: USD 20.0000

Min.Order :1 Metric Ton
Purity: 99
Payment Terms : L/C,T/T

Keywords

849217-64-7 Foretinib (GSK1363089) C34H34F2N4O6

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Appearance:powder
Application:medical
PackAge:As required
ProductionCapacity:20|Metric Ton|Day
Storage:room tempurature
Transportation:accordingly

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Product Name: Foretinib (GSK1363089)

Synonyms: Foretinib;GSK 1363089;EXEL-2880;XL880;N-[3-Fluoro-4-[[6-(methyloxy)-7-[[3-(morpholin-4-yl)propyl]oxy]quinolin-4-yl]oxy]phenyl]-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;N-[3-Fluoro-4-[[6-methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinolinyl]oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide;XL880(GSK1363089);foretinib N1-{3-fluoro-4-[(6-(Methyloxy)-7-{[3-(4-Morpholinyl)propyl]oxy}-4-quinolinyl)oxy]phenyl}-N1'-(4-fluorophenyl)-1,1-cyclopropanedicarboxaMide

CAS: 849217-64-7

MF: C34H34F2N4O6

MW: 632.6537664

EINECS:

Product Categories: Inhibitors

Mol File: 849217-64-7.mol

Foretinib (GSK1363089) Structure

Foretinib (GSK1363089) Chemical Properties

density 1.372

Safety Information

MSDS Information

Foretinib (GSK1363089) Usage And Synthesis

Description Foretinib (GSK1363089) is an ATP-competitive inhibitor of HGFR and VEGFR, mostly for Met and KDR with IC50 of 0.4 nM and 0.9 nM in cell-free assays. Less potent against Ron, Flt-1/3/4, Kit, PDGFRα/β and Tie-2, and little activity to FGFR1 and EGFR. Phase 2.

Uses XL880 (GSK1363089, EXEL-2880) is an ATP-competitive inhibitor of MET and KDR with IC50 of 0.4 nM and 0.9 nM, respectively.

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