Competitive Price 9...

Competitive Price 99% Active Pharmaceutical Ingredients Gliquidone For Antidiabetic CAS NO.33342-05-1
Competitive Price 99% Active Pharmaceutical Ingredients Gliquidone For Antidiabetic CAS NO.33342-05-1
Competitive Price 99% Active Pharmaceutical Ingredients Gliquidone For Antidiabetic CAS NO.33342-05-1
Competitive Price 99% Active Pharmaceutical Ingredients Gliquidone For Antidiabetic CAS NO.33342-05-1
Competitive Price 99% Active Pharmaceutical Ingredients Gliquidone For Antidiabetic CAS NO.33342-05-1

Competitive Price 99% Active Pharmaceutical Ingredients Gliquidone For Antidiabetic CAS NO.33342-05-1

Min.Order / FOB Price:Get Latest Price

1 Gram

FOB Price: USD 1.0000

  • Min.Order :1 Gram
  • Purity: 99% min
  • Payment Terms : T/T,

Keywords

Gliquidone Glurenorm ardf26

Quick Details

  • Appearance:White crystallized powder
  • Application:medical pharmaceutical
  • PackAge:al foil bag
  • ProductionCapacity:1000|Kilogram|Month
  • Storage: Kept in a well-closed, light-resistant, dry and cool place
  • Transportation: Kept in a well-closed, light-resistant, dry and cool place

Superiority:

1, High quality with competitive price: 
1)Purity≥ 99% 
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Details:

Details

 

99% Active Pharmaceutical Ingredients Gliquidone For Antidiabetic
 
 
Quick Detail
Product Name
 
Gliquidone
 
Synonym
 
ardf26;ardf26se;Gliquidone;Glurenorm
 
CAS NO
 
33342-05-1
 
MF
 
C27H33N3O6S
 
MW
 
527.63
 
EINECS
 
251-463-2
 
Purity
 
99%
 
Appearance
 
White powder
 

Grade

Pharma Grade

Melting Point
 
168-173º C
 
Usage
 
Antidiabetic
 
Package
 
1kg/foil bag
 
 
 
Description:
 
Gliquidone is an anti-diabetic drug in the sulfonylurea class. In patients with diabetes mellitus, there is a deficiency or absence of a hormone manufactured by the pancreas called insulin. Insulin is the main hormone responsible for the control of sugar in the blood. Gliquidone is an antidiabetic medication which is used in those patients with adult maturity onset or non-insulin dependent diabetes (NIDDM). It works by lowering blood sugar levels by stimulating the production and release of insulin from the pancreas. It also promotes the movement of sugar from the blood into the cells in the body which need it.
 
 
Mechanism of Action:
 
The mechanism of action of gliquidone in lowering blood glucose appears to be dependent on stimulating the release of insulin from functioning pancreatic beta cells, and increasing sensitivity of peripheral tissues to insulin. Gliquidone likely binds to ATP-sensitive potassium channel receptors on the pancreatic cell surface, reducing potassium conductance and causing depolarization of the membrane. Membrane depolarization stimulates calcium ion influx through voltage-sensitive calcium channels. This increase in intracellular calcium ion concentration induces the secretion of insulin.
 
 
Usage:
 
1. Hypoglycemic drugs, for the treatment of mild, non insulin dependent diabetes mellitus.
 
2. Glibenclamide and glibenclamide, glibenclamide, which belongs to the second generation oral sulfonylurea drugs,with the mechanism of toluene sulfonyl Ding Niao, its hypoglycemic effect was the strongest sulfonylurea, intensity for tolbutamide 200~250 times. Be selective effect on pancreatic beta cells, promote the secretion of insulin, can enhance the hypoglycemic effect of exogenous insulin, insulin receptor after strengthening effect.
 
3. Glibenclamide is one of the drugs currently used to treat type 2 diabetes, the most often used, because the utility function is fast and strong, so after the application has obvious effect, can effectively control blood sugar, high blood sugar, is applicable to other sulfonylurea hypoglycemic effect not beautiful person.
 

 

 

 

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