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Nimesulide 51803-78-2 Nimesulide powder
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Product Name: | Nimesulide |
Synonyms: | nimed;4-NITRO-2-PHENOXYMETHANE SULPHONANILIDE;MESULID;AULIN;FANSIDOL;CETIRIZINE DIHYDROCHLORIDE EPC(CRM STANDARD);CETIRIZINE DIHYDROCHLORIDE IMP. E (EP):(RS)-2-[2-[2-[4-[(4-CHLOROPHENYL)-PHENYLMETHYL]PIPERAZIN-1-YL]ETHOXY]ETHOXY]ACETIC ACID MM(CRM STANDARD);CETIRIZINE DIHYDROCHLORIDE MM(CRM STANDARD) |
CAS: | 51803-78-2 |
MF: | C13H12N2O5S |
MW: | 308.31 |
EINECS: | 257-431-4 |
Product Categories: | Active Pharmaceutical Ingredients;All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Aromatics;Isotope Labelled Compounds;Sulfur & Selenium Compounds;Other APIs |
Mol File: | 51803-78-2.mol |
Nimesulide Chemical Properties |
mp | 140-146°C |
storage temp. | 2-8°C |
Stability: | Stable. Incompatible with strong oxidizing agents. |
CAS DataBase Reference | 51803-78-2(CAS DataBase Reference) |
Safety Information |
Hazard Codes | Xn,Xi |
Risk Statements | 22-36/37/38 |
Safety Statements | 36-26 |
RIDADR | UN 2811 6.1/PG 3 |
WGK Germany | 3 |
RTECS | PB0970000 |
MSDS Information |
Provider | Language |
---|---|
Nimesulide | English |
SigmaAldrich | English |
Nimesulide Usage And Synthesis |
Chemical Properties | Yellow Needle-Like Crystals |
Usage | Antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-alpha production |
Usage | Labelled Nimesulide (N477500). Antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-α production. |
Usage | Antiinflammatory;'Cyclooxygenase 2 inhibitor |
Usage | For the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old. |
Usage | Labelled Nimesulide . Antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-α production.;Labeled Nimesulide, intended for use as an internal standard for th |
Biological Activity | Selective, orally active cyclooxygenase-2 (COX-2) inhibitor. Produces potent analgesic, anti-inflammatory and antipyretic activities in vivo . Reported to produce fewer gastrointestinal side effects than standard NSAIDs |
Product Name: | Nimesulide |
Synonyms: | nimed;4-NITRO-2-PHENOXYMETHANE SULPHONANILIDE;MESULID;AULIN;FANSIDOL;CETIRIZINE DIHYDROCHLORIDE EPC(CRM STANDARD);CETIRIZINE DIHYDROCHLORIDE IMP. E (EP):(RS)-2-[2-[2-[4-[(4-CHLOROPHENYL)-PHENYLMETHYL]PIPERAZIN-1-YL]ETHOXY]ETHOXY]ACETIC ACID MM(CRM STANDARD);CETIRIZINE DIHYDROCHLORIDE MM(CRM STANDARD) |
CAS: | 51803-78-2 |
MF: | C13H12N2O5S |
MW: | 308.31 |
EINECS: | 257-431-4 |
Product Categories: | Active Pharmaceutical Ingredients;All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Aromatics;Isotope Labelled Compounds;Sulfur & Selenium Compounds;Other APIs |
Mol File: | 51803-78-2.mol |
Nimesulide Chemical Properties |
mp | 140-146°C |
storage temp. | 2-8°C |
Stability: | Stable. Incompatible with strong oxidizing agents. |
CAS DataBase Reference | 51803-78-2(CAS DataBase Reference) |
Safety Information |
Hazard Codes | Xn,Xi |
Risk Statements | 22-36/37/38 |
Safety Statements | 36-26 |
RIDADR | UN 2811 6.1/PG 3 |
WGK Germany | 3 |
RTECS | PB0970000 |
MSDS Information |
Provider | Language |
---|---|
Nimesulide | English |
SigmaAldrich | English |
Nimesulide Usage And Synthesis |
Chemical Properties | Yellow Needle-Like Crystals |
Usage | Antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-alpha production |
Usage | Labelled Nimesulide (N477500). Antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-α production. |
Usage | Antiinflammatory;'Cyclooxygenase 2 inhibitor |
Usage | For the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old. |
Usage | Labelled Nimesulide . Antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-α production.;Labeled Nimesulide, intended for use as an internal standard for th |
Biological Activity |
Selective, orally active cyclooxygenase-2 (COX-2) inhibitor. Produces potent analgesic, anti-inflammatory and antipyretic activities in vivo . Reported to produce fewer gastrointestinal side effects than standard NSAIDs |
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