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100% Natural 7-Ethyl-10-hydroxycamptothecin 7-Ethyl-10-hydroxycamptothecin Manufacturer For The Preparation Of Irinotecan Hydrochloride
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7-Ethyl-10-hydroxycamptothecin Basic information |
Product Name: | 7-Ethyl-10-hydroxycamptothecin |
Synonyms: | 7-10-hydroxycamptothecin;(4S)-4,9-Dihydroxy-4,11-diethyl-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;(4S)-4,9-Dihydroxy-4α,11-diethyl-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-dione;EHCPT;7-Ethyl-10-hydroxy-CPT (Camptothecine), SN-38;10-Hydroxycamptothecin acetate salt ,99%;Irinotecan Related Compound B (10 mg) ((S)-4,11-diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione);(S)-4,11-diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione |
CAS: | 86639-52-3 |
MF: | C22H20N2O5 |
MW: | 392.4 |
EINECS: | 1592732-453-0 |
Product Categories: | Antitumors for Research and Experimental Use;Biochemistry;Natural Plant Extract;Chiral Reagents;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Natural Anti-cancer Medical Materials and It's Derivatives;Pharmaceutical Raw Materials;Miscellaneous Natural Products;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Chiral Reagents, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals;Inhibitors |
Mol File: | 86639-52-3.mol |
7-Ethyl-10-hydroxycamptothecin Chemical Properties |
Melting point | 217 °C |
refractive index | 21.5 ° (C=0.2, THF) |
storage temp. | −20°C |
solubility | DMSO: soluble1mg/mL |
CAS DataBase Reference | 86639-52-3(CAS DataBase Reference) |
Safety Information |
Hazard Codes | T |
Risk Statements | 25 |
Safety Statements | 45 |
RIDADR | 2811 |
RTECS | UQ0491000 |
HazardClass | 6.1 |
PackingGroup | Ⅲ |
7-Ethyl-10-hydroxycamptothecin Usage And Synthesis |
Chemical Properties | Light-Yellow Solid |
Uses | A metabolite of Irinotecan, a DNA topoisomerase inhibitor |
Definition | ChEBI: A member of the class of pyranoindolizinoquinolines that is (4S)-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-dione bearing two additional ethyl substituents at positions 4 and 11 as well as two additional hydroxy substitu nts at positions 4 and 9. It is the active metabolite of irinotecan and is ~1000 times more active than irinotecan itself. |
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