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TIANFUCHEM--103300-74-9---Taltirelin TIANFUCHEM--103300-74-9---Taltirelin TIANFUCHEM--103300-74-9---Taltirelin
CAS 103300-74-9 Taltirelin Acetate
Taltirelin is a synthetic thyrotropin-releasing hormone (TRH) analog. Displays ~ 30-100-fold more potent CNS activity and ~ 50-fold weaker endocrine activity than TRH. Both antinociceptive and neuroprotective.
Product Name: Taltirelin
CAS: 103300-74-9
MF: C17H23N7O5
MW: 405.41
Product Categories: Peptide;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Neurochemicals;Pharmaceuticals
Uses: Analog of thyrotropin releasing hormone TRH, with pronounced CNS activity. Used in the treatment of spinocerebellar degeneration.
Item | Standard | |
Identification |
A.H-NMR:Comply with the structure |
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B.LC-MS:Comply with the structure |
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C.The IR spectrum of sample should be identical with that of reference standard; |
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D.HPLC-ESI-MS The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay. |
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Crystallinity |
meets the requirements. |
|
Loss on drying |
≤2.0% |
|
Heavy metals |
≤10 ppm |
|
Water |
≤1.0% |
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Sulphated ash |
≤0.5%, determined on 1.0 g. |
|
Related substances |
Unspecified impurities: for each impurity |
≤0.10% |
Total Impurity |
≤0.5% |
|
Purity |
≥99.0% |
|
Assay |
99.0%~101.0% (anhydrous substance). |
|
Microbiological Analysis |
||
Total plate count |
≤1000cfu/g |
|
Yeast and Moulds |
≤100cfu/g |
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E. Coli. |
Absent |
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Salmonella |
Absent |
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S.aureus |
Absent |
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Storage |
Preserve in well-closed, light-resistant and airtight containers. |
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