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Deflazacort Deflazacort powder CAS 14484-47-0
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Product Name: |
Deflazacort |
Synonyms: | 16-d)oxazole-3,20-dione,11-beta,21-dihydroxy-2’-5’-beta-h-pregna-4-dieno(17;azacort;calcort;deflan;dl-458-it;l-5458;lantadin;DEFLAZACORT |
CAS: | 14484-47-0 |
MF: | C25H31NO6 |
MW: | 441.52 |
EINECS: | 238-483-7 |
Product Categories: |
Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;Steroid and Hormone;CALCORT |
Mol File: | 14484-47-0.mol |
Molecular structure: |
Function
Pharmaceutical raw materials, the third generation of corticosteroids, anti-inflammatory, anti-allergy, increased gluconeogenesis and so on; for primary and secondary adrenocortical insufficiency, rheumatism, collagen diseases, skin diseases, allergic disease, eye disease, fulminant and disseminated tuberculosis, hematopoietic system disorders, etc.
COA
Items |
Standard |
Results |
Description |
White crystalline powder |
white crystalline powder |
Identification(IR,UV,HPLC) |
Complies with the standard |
complies |
Solubility test |
Freely soluble in acetic acid, methylene chloride, slightly soluble in ethanol, acetone,methanol, insoluble in water |
complies |
Melting point |
255~258°C |
255.0~256.0°C |
Loss on drying |
no more than 0.5% |
0.05% |
Water |
no more than 0.5% |
0.18% |
Specific rotation |
+58°~+62° |
+61.2° |
Heavy metals |
no more than 10 ppm |
complies |
Sulphated ash |
no more than 0.1% |
0.05% |
Individual impurity |
no more than 1.0% |
0.53% |
Total impurities |
no more than 2.0% |
1.1% |
Assay |
97.0%~102.0% |
99.7% |
Residual solvents |
Methanol NMT 300 ppm |
complies |
Dichioromethane NMT 600 ppm |
complies |
|
Ethyl acetate NMT 500ppm |
complies |
Packing and shipping
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