7-Dehydrocholesterol Manufacturer 434-16-2 Vitamin D3 Intermediates

Details :

product name: 7-dehydrocholesterol
synonyms: (3)-7-dehydrochlesterol;(3beta)-cholesta-5,7-dien-3-ol;(3-beta)-cholesta-7-dien-3-ol;(3beta)-cholesta-7-dien-3-ol;3-hydroxycholesta-5,7-diene;5,7-cholestandien-3.beta.-ol;5,7-cholestandien-3beta-ol;7,8-didehydrocholesterol
product details:
place of origin: china
certification: iso9001
brand:yuancheng
payment & shipping terms:

minimum order quantity:1kg
supply ability:500kg/week
delivery time:within 24 hours after payment
payment terms:, moneygram, t/t
appeatance:white to off-white fine crystalline powder

product description:
cas: 434-16-2
mf: c27h44o
mw: 384.64
einecs: 207-100-5
package:25kg/bucket
purity:95%

7-dehydrocholesterol is a zoosterol that functions in the serum as a cholesterol precursor, and is converted to vitamin d3 in the skin, therefore functioning as provitamin-d3. the presence of this compound in human skin enables humans to manufacture vitamin d3 from ultra-violet rays in the sun light, via an intermediate isomer pre-vitamin d3. it is also found in the milk of several mammalian species. in insects it is a precursor for the hormone ecdysone, required for reaching adulthood.it was discovered by nobel-laureate organic chemist adolf windaus

synthesis of pre-vitamin d3 in the skin involves uvb radiation which effectively penetrates only the epidermal layers of skin. 7-dehydrocholesterol absorbs uv light most effectively at wavelengths between 290-320nm and thus the production of vitamin d3 will only occur at those wavelengths. the two most important factors that govern the generation of pre-vitamin d3 are the quantity (intensity) and quality (appropriate wavelength) of the uvb irradiation reaching the 7-dehydrocholesterol deep in the stratum basale and stratum spinosum.[4] another important consideration is the quantity of 7-dehydrocholesterol present in the skin. under normal circumstances, ample quantities of 7-dehydrocholesterol (about 25-50 mg/cm2 of skin) are available in the stratum spinosum and stratum basale of human skin to meet the body's vitamin d requirements.

usage:
1. important intermediate in the synthesis of vitamin d3
2. skin sunscreen additive in cosmetics
3. other laboratory reagents