Ceritinib

Ceritinib

Ceritinib

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1 Gram

Negotiable

  • Min.Order :1 Gram
  • Purity: 98%
  • Payment Terms : L/C

Keywords

Ceritinib 1032900-25-6 5-Chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine， LDK378,Zykadia,1380575-43-8 (2HCl), 1190399-48-4 (xHCl)

Quick Details

  • Appearance:Solid Powder
  • Application:research use
  • PackAge:inquiry
  • ProductionCapacity:10|Kilogram|Month
  • Storage:
  • Transportation:inquiry

Superiority:

We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. #

Details:

An anaplastic lymphoma kinase (ALK)-positive inhibitor used for the treatment of non-small cell lung cancer (NSCLC). It less potently inhibits IGF-1R, InsR, and STK22D and IC50 value is 8, 7, and 23 nM. LDK378 is also minimally effective against a panel of other kinases. In Sep 2016, Interim adverse events and efficacy data from phase III ASCEND-4 trial in non small cell lung cancer released by Novartis. In Oct 2016, efficacy data from the phase III ASCEND-3 and ASCEND-5 trial in non small cell lung cancer was presented.

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