high purity and high quality of Dasatinib monohydrate with best price

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We supply high purity and high quality of Dasatinib monohydrate with best price.

Dasatinib Intermediate/CAS 863127-77-9/Dasatinib

Product Description

Basic Information:

Product name:  Dasatinib monohydrate

Cas Number:   863127-77-9           

Molecular Formula: C22H26ClN7O2S.H2O

Molecular Weight: 506.02

Dasatinib monohydrate is more effective than imatinib in inhibiting the proliferation of Ba/F3 cells expressing wild-type Bcr-Abl and Bcr-Abl mutants, with the exception of T315I. Dasatinib monohydrate has a two-log (∼325-fold) increased potency relative to imatinib. Dasatinib monohydrate potently inhibits wild-type Abl kinase and all mutants except T315I over a narrow range. Dasatinib monohydrate directly targets wild-type and mutant Abl kinase domains and inhibits autophosphorylation and substrate phosphorylation in a concentration-dependent manner.

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Thanks to the professional chemists and engineers hard-work spirit, we successfully develop some applicable intermediates and specialty raw materials for our principal needs. Our laboratories combined the institute research ability and fine chemical plants capacity to make a total newly research and development area.

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