High Quality Isorhapontigenin / Isorhapotigenin / Isorhapotogenin

Details:

We produce the Isorhapontigenin powder:

Specification:

CAS No: 32507-66-7

Molecular Formula: C15H14O4

Molecular Weight: 258.27

Specifications: ≥98%(HPLC)

Appearance: Off white or light yellow powder

Mp: 175-180°C

We have enough stock in factory

Introduction:

Isorhapontigenin is a tetrahydroxylated stilbenoid with a methoxy group. It is an isomer of rhapontigenin and an analog of resveratrol. It is found in the Chinese herb Gnetum cleistostachyum, in Gnetum parvifolium and in the seeds of the palm Aiphanes aculeata.

An isorhapontigenin tetramer, gnetuhainin R, can be isolated from the lianas of Gnetum hainanense.

Isorhapontin, the isorhapontigenin glucoside, can be found in spruce species such as the Norway spruce (Picea abies), the sitka spruce (Picea sitchensis) and the white spruce (Picea glauca).

Main functions:

Isorhapontigenin (ISO) is a new derivative of stilbene isolated from the Chinese herb Gnetum cleistostachyum. Our recent studies have revealed that ISO treatment at doses ranging from 20 to 80 uM triggers apoptosis in multiple human cancer cell lines. In the present study, we evaluated the potential effect of ISO on autophagy induction. We found that ISO treatment at sublethal doses induced autophagy effectively in human bladder cancer cells, which contributed to the inhibition of anchorage-independent growth of cancer cells. 

Applications:

1.Applied in food field, often used as additives, with distinct fragrance smell, it can promote digestion and increase appetite;

2.Applied in daily necessities field, aslo added into a large amount of oral cleaning products, such as dentifrices, mouthwash and tooth powder;

3.Applied in pharmaceutical field, because of the function of inhibition and paralysis to sensory nerve endings, it can be used as counter irritant.

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