Mecobalamin,cas:13422-55-4 Mecobalamin Mecobalamin Mecobalamin Mecobalamin Mecobalamin Mecobalamin
Methylcobalamin (mecobalamin, MeCbl, or MeB12) is a cobalamin, a form of vitamin B12. It differs from cyanocobalamin in that the cyanide is replaced by a methyl group.[1] Methylcobalamin features an octahedral cobalt(III) centre. Methylcobalamin can be obtained as bright red crystals.[2] From the perspective of coordination chemistry, methylcobalamin is notable as a rare example of a compound that contains metal-alkyl bonds. Nickel-methyl intermediates have been proposed for the final step of methanogenesis.
Methylcobalamin is equivalent physiologically to vitamin B12, and can be used to prevent or treat pathology arising from a lack of vitamin B12 (vitamin B12 deficiency), such as pernicious anemia.
Methylcobalamin is also used in the treatment of peripheral neuropathy,diabetic neuropathy, and as a preliminary treatment for amyotrophic lateral sclerosis.
Systematic (IUPAC) name | |
---|---|
carbanide; cobalt(3+); | |
Clinical data | |
AHFS/Drugs.com | International Drug Names |
Pregnancy cat. | |
Legal status | OTC (US) |
Routes | oral,sublingual,injection. |
Identifiers | |
CAS number | 13422-55-4 |
ATC code | B03BA05 |
PubChem | CID 6436232 |
UNII | BR1SN1JS2W |
ChEMBL | CHEMBL1697757 |
Chemical data | |
Formula | C63H91CoN13O14P |
Mol. mass | 1344.40 g/mol |
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