10 Gram	FOB Price:USD 12.0000 -14.0000

Min.Order :10 Gram
Purity: ≧99.5%
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179474-81-8 Prucalopride|5-HT4A and 5-HT4B receptor agonist China Prucalopride(179474-81-8) factory Sell high quality 179474-81-8 99% produced in China factory

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Appearance:white powder
Application:used for research
PackAge:As customer request
ProductionCapacity:100|Metric Ton|Day
Storage:Store in a cool,dry place and keep away from direct strong light
Transportation:Common products:Sea/Air/Courier Dangerous Chem:Sea/Air

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PRODUCT NAME :Prucalopride

CAS NUMBER: 179474-81-8
Other name:R 093877;R093877;Resolor;Unii-0A09iuw5tp;Prucalopride(R-93877)

Prucalopride(179474-81-8)was a highly selective serotonin receptor agonist which could improve bowel functions,

including number of bowel movements and a range of other constipation symptoms,as well as health-related quality of life and patient satisfaction.The most common adverse events were headache,diarrhoea,nausea,abdominal pain,etc

Details:

Prucalopride

PRODUCT NAME :Prucalopride
STRUCTURE
CAS NUMBER: 179474-81-8
MOLECULAR FORMULA C18H26ClN3O3
MOLECULAR WEIGHT 367.874
BATCH NO. 201711002

Prucalopride(179474-81-8)was a highly selective serotonin receptor agonist which could improve bowel functions,

including number of bowel movements and a range of other constipation symptoms,as well as health-related quality of life and patient satisfaction.The most common adverse events were headache,diarrhoea,nausea,abdominal pain,etc

Mete-analysis showed that the efficacy rate was significantly higher in prucalopride(179474-81-8)group （29.2%） than in the placebo group （12.6%, RR=2.37, 95% CI 2.02-2.79, P〈0.001）, while it was similar to that of PEG 3350＋electrolytes group. The incidence rates of headache, dizziness, diarrhea, abdominal pain, and nausea were higher in the prucalopride group than in the placebo group （P≤ 0.05）. There were no differences in the incidence of flatulence and prolonged Q T interval between the two groups （P〉0.05）. Conclusion Prucalopride is effective in the treatment of CC, with relatively milder and lower incidence of adverse reaction, and it could be a new choice for the treatment of CC.

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Specification

Test Item Criteria Prescribe

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Characteristics White to off-white powder
Water 4.0~6.0%
Melting point 100~110
Single impurity ≦0.1%
Purity ≧99.5%
Solvent residue Methanol≦0.3%, Ethyl Alcohol≦0.5% ,THF≦0.072%