Tacrolimus FK-506 with lower price

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1 Kilogram	FOB Price: USD 1.0000

1 Kilogram

FOB Price: USD 1.0000

Tacrolimus FK-506 104987-11-3 Apis

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tacrolimus usage and synthesis

chemical properties	white crystalline solid
usage	an immunosuppressant that blocks t cell proliferation in vitro by inhibiting the generation of several lymphokines, especially il-2. shown to inhibit the activity of fk-506 binding protein, thereby reversing its effects on sarcoplasmic reticulum ca+2 release.
usage	fk-506 (tacrolimus) is a macrolide immunosuppressive drug that is mainly used after allogeneic organ transplant to reduce the activity of the patient's immune system
usage	tacrolimus (fujimycin) was discovered as a potent inhibitor of il2 production in a targeted search for novel immunosuppressants. tacrolimus acts by blocking t cell proliferation in vitro by inhibiting the generation of several lymphokines, notably the original target il-2. tacrolimus inhibits the activity of fk-506 binding protein, ca2+-dependent phosphatase and calcineurin, and activates nf-κb through phosphorylation and degradation of iκbα.
usage	treatment of cushing's syndrome
usage	for use after allogenic organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. it was first approved by the fda in 1994 for use in liver transplantation, this has been extended to include kidney, heart,