EGF / Epidermal Growth Factor

Details:

 

 

Name: Recombinant human epidermal growth factor (rhEGF)
CAS No.: 62253-63-8
INCI Name: Human Oligopeptide-1
Source: E. coli
Endotoxin level: less than 0.1 ng per μg (1EU/ug).

 

 

 

 

 

 

Item	Specification
Appearance	White lyophilized powder
Purity, % (by RP-HPLC)	98.1%
Activity unit	8.0 x 105 IU/mg
pH value	7.2
Isoelectric point	4.8
Water residue	1.8%
Identification test	Positive
Sterility test	No bacterial growth
Abnormal toxicity exp.	The tested animals have no abnormal reactions. They keep healthy and have weight increase.

 

 

  

 

[Applicatin]

EGF secreted by each of us, when we were in child times the secretion is the highest, and then it decreased with age increases. Particularly, After 22 years of age, reduced secretion was more pronounced. When we use cosmetics containing EGF, absorbed through the skin, added EGF of our skin exogenously, so that it can make our skin to restore the young state.
We use E.coli by genetic engineering expressed, produced high purity EGF by biological fermentation. It was named Recombinant human epidermal growth factor (rhEGF). rhEGF have same structure with Human epidermal growth factor (EGF), it is a 6.2kDa protein.
EGF stimulates the proliferation and differentiation of epithelial cells from skin, the cornea, lung and tracheal tissue and the gastrointestinal tract. EGF also promotes the proliferation of fibroblasts and embryonic cells. Thus, EGF plays an important role in wound healing and organogenesis.
EGF is a highly efficient cell division factor with many other biological effects, which mainly includes: 
 

1. stimulating the growth and proliferation of skin, cornea and tracheal epithelium tissue in vivo. 
2. Accelerating the healing process of epidermis damage on skin, cornea, etc. 
3. Repressing the gastric acid excretion. 
4. elerating the proliferation of epithelial cells in human and animals. 
5. Facilitating the biosynthesis of protein, RNA, DNA as well as metabolic activity in epidermal cells.

 

[Usage] 

First of all, put the EGF dissolved in distilled water. Wait the temperature of cosmetic cream decreased to below 40 degrees Celsius, then put the dissolved solution into the cream, stir the cream to full blending them.

 

 

 

 

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Binbo Biological Co., Ltd. is located in the convenient transportation and beautiful scenery of Jining high-technology industrial zone - Jinxiang economic Development Zone. There is a 105 National road links north and south when Zaocao and Dongfeng Roads connect east and west. Besides, provincial expressway and Ji-Xu expressway which connect Beijing,Shanghai,Fuzhou, and several cities across the JinXiang economic development zone. More importantly, there are only 20 km to Jining airport and close to Qufu high-speed railway station.These convenient geographical conditions bring the development opportunities for this economic development zone.

Binbo Biological Products Co. Ltd., is a professional high-tech enterprise which engaged in Biological products raw materials. Company was established in 2001, currently our company has more than 28 thousand square meters covering area. Factory buildings and workshops were establishsd by modern production requirements.There are three steps of development project which planned to invest around 60 million RMB. Currently the first step were finished and spent 28 million RMB, which met the production and office requirements.

Binbo is engaged in R&D with perfect equipments and advanced detecting instruments. The factory is in strict accordance with GMP standard in the course of design and construction.

 

 

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