Tetracaine hydrochloride / Tetracaine HCL CAS 136-47-0

Details:

 

 

cas no. 136-47-0

chemical name: tetracaine hydrochloride

synonyms: anacel;tonexol;decicain;anethaine;curtacain;decicaine;menonasal;pantocaine;butethanol;gingicainm

cbnumber: cb1373091

molecular formula: c15h25cln2o2

formula weight: 300.82

mol file: 136-47-0.mol

tetracaine hydrochloride property

melting point : 149°c

storage temp. : refrigerator

merck : 9188

cas database reference: 136-47-0(cas database reference)

epa substance registry system: benzoic acid, 4-(butylamino)-, 2-(dimethylamino)ethyl ester, monohydrochloride(136-47-0)

tetracaine hcl

synonyms: tetracaine hydrochloride; 4-(butylamino)benzoic acid 2-(dimethylamino)ethyl ester hydrochloride

cas: 136-47-0

einecs: 205-248-5

assay: 98.0%-101.0%

standard: usp32

packing: 1kg/foil bag; 25kg/cardboard drum

mf: c15h25cln2o2

mw: 300.82

 

 

it's mainly used as a local anesthetic drug. the effect of local anesthesia is stronger than that of procaine, and it is more toxic. it can penetrate the mucous membrane and is mainly used for mucosal anesthesia.

dosage(for reference):

1% solution spraying or smearing

infiltration local anesthesia, 0.025 ~ 0.03% solution

nerve conduction block, 0.1 ~ 0.3% solution

epidural block 0.15 ~ 0.3% solution

when combine with lidocaine hydrochloride, the highest concentration is 0.3%.

 

 

 

 

 

 

product name	tetracaine hydrochloride
cas no.	136-47-0	outer packing		25kg/drum
production date	2016/12/5	shelf life		2018/12/4
standard	usp
items of analysis	specification		results
description	white to white crystalline powder		complies
identification	a/b/c meets the requirements accordingly		complies
related substance	not exceeding 0.05% of the reference solution		complies
ph	4.5-6.5		4.8
ignition residue	≤0.100		0.08%
water	≤0.5%		≤0.10%
loss on drying	≤0.5%		≤0.10%
heavy metal	≤0.10%ppm		complies
sulfate grey powder	≤0.10%		≤0.02%
assay	98.5%-101%		100.07%

 

  

 

tetracaine (inn, also known as amethocaine; trade name pontocaine. ametop and dicaine) is a potent local anesthetic of the ester group. it is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.

 

in biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. tetracaine is an allosteric blocker of channel function. at low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.

 

 

 

 

 

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Binbo Biological Co., Ltd. is located in the convenient transportation and beautiful scenery of Jining high-technology industrial zone - Jinxiang economic Development Zone. There is a 105 National road links north and south when Zaocao and Dongfeng Roads connect east and west. Besides, provincial expressway and Ji-Xu expressway which connect Beijing,Shanghai,Fuzhou, and several cities across the JinXiang economic development zone. More importantly, there are only 20 km to Jining airport and close to Qufu high-speed railway station.These convenient geographical conditions bring the development opportunities for this economic development zone.

Binbo Biological Products Co. Ltd., is a professional high-tech enterprise which engaged in Biological products raw materials. Company was established in 2001, currently our company has more than 28 thousand square meters covering area. Factory buildings and workshops were establishsd by modern production requirements.There are three steps of development project which planned to invest around 60 million RMB. Currently the first step were finished and spent 28 million RMB, which met the production and office requirements.

Binbo is engaged in R&D with perfect equipments and advanced detecting instruments. The factory is in strict accordance with GMP standard in the course of design and construction.

 

 

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