Aprotinin

Details:

 

 

Source: Bovine Lungs

Generaldescription

White or almost white powder ,also known astrypsin inhibitors.  Molecular formula C284H432N84O79S7,molecular weight of 6511.52 g/mol. 1 unit Aprotinin can make 0.8μg methyltrypsin inactivation. Aprotinin is a polypeptide consisting of a chain offifty-eight amino acids. Soluble in water, and can keep stable on neutral andacidic conditions, but denatured on alkalineconditions.

It inhibits the activity of severalproteolytic enzymes such as chymotrypsin, kallikrein, plasmin and trypsin, preventother active protease and trypsinogen was activated in the pancreas ,etc.

 

 

 

 

   

Item	Specification	Standard
Apperance	White or almost white powder	Enterprise Standard
Identification	Conform	Enterprise Standard
Appearance of solution	Clear	Enterprise Standard
PH	5.0-7.0	Enterprise Standard
Loss on drying	≤6.0%	Enterprise Standard
Absorbance	≤0.8（277nm）	Enterprise Standard
Macromolecular proteins	≤3.0%	Enterprise Standard
Bacterial endotoxins	Conform	Enterprise Standard
Histamine	Conform	Enterprise Standard
Abnormal toxicity	Conform	Enterprise Standard
Assay	Not less than 3.0 units/mg, calculated on the dried basis.	Enterprise Standard

 

 

 

--In clinical, used in the prevention andtreatment of acute pancreatitis, hemorrhage and disseminated intravascularcoagulation caused by fibrinolysis.

--It can prevent or delay the developmentof pulmonary interstitial edema (shock lung), and its inhibition has a dose andtime dependent.

--After abdominal surgery, injected directlyinto the abdominal cavity can prevent intestinal adhesion.

 

 

 

 

 

 

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Binbo Biological Co., Ltd. is located in the convenient transportation and beautiful scenery of Jining high-technology industrial zone - Jinxiang economic Development Zone. There is a 105 National road links north and south when Zaocao and Dongfeng Roads connect east and west. Besides, provincial expressway and Ji-Xu expressway which connect Beijing,Shanghai,Fuzhou, and several cities across the JinXiang economic development zone. More importantly, there are only 20 km to Jining airport and close to Qufu high-speed railway station.These convenient geographical conditions bring the development opportunities for this economic development zone.

Binbo Biological Products Co. Ltd., is a professional high-tech enterprise which engaged in Biological products raw materials. Company was established in 2001, currently our company has more than 28 thousand square meters covering area. Factory buildings and workshops were establishsd by modern production requirements.There are three steps of development project which planned to invest around 60 million RMB. Currently the first step were finished and spent 28 million RMB, which met the production and office requirements.

Binbo is engaged in R&D with perfect equipments and advanced detecting instruments. The factory is in strict accordance with GMP standard in the course of design and construction.

 

 

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