Octreotide

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Octreotide is a synthetic octapeptide cyclic compound. It is a homologue of natural somatostatin and has the pharmacological activity of natural somatostatin. It has a long-acting effect (The half-life of this product is 1.5 hours, while natural somatostatin is 2 to 3 minutes). This product has a selective inhibitory effect on the secretion of growth hormone, glucagon, and insulin, and has a stronger effect than natural somatostatin. It has been proved by animal experiments that the inhibition of growth hormone release is natural growth after intravenous injection of this product for 15 minutes. 70 times of somatostatin, insulin inhibition is 3 times that of natural somatostatin. It also has an inhibitory effect on thyrotropin, adrenocorticotropic hormone, gastrin, cholecystokinin, and intestinal vasoactive peptides, and can inhibit the secretion of gastric acid, pancreatic amylase, lipase, and pepsin. Can slow down the passage time of gastrointestinal tract, promote the absorption of water and electrolytes, have a contraction effect on visceral blood vessels, can reduce blood flow to the viscera, reduce liver blood flow, reduce portal pressure and portal blood flow, reduce intestinal overgrowth Secretion, and can enhance the intestinal absorption of water and Na +.

 

 

 

 

 

   

product name	Octreotide
assay	99.0% to 101.0%	99.9%
melting point	----	----
loss on drying	0.5%max.	0.22%
sulphated ash	0.1%max.	0.05%
acidity	0.01m naoh<0.50ml	0.39

 

 

 

 

Octreotide is also used to treat a certain condition (acromegaly) that occurs when the body makes too much of a certain natural substance called growth hormone. Treating acromegaly helps reduce the risk of serious problems such as diabetes and heart disease. Octreotide works by decreasing the amount of growth hormone to normal levels.

 

 

 

 

 

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Binbo Biological Co., Ltd. is located in the convenient transportation and beautiful scenery of Jining high-technology industrial zone - Jinxiang economic Development Zone. There is a 105 National road links north and south when Zaocao and Dongfeng Roads connect east and west. Besides, provincial expressway and Ji-Xu expressway which connect Beijing,Shanghai,Fuzhou, and several cities across the JinXiang economic development zone. More importantly, there are only 20 km to Jining airport and close to Qufu high-speed railway station.These convenient geographical conditions bring the development opportunities for this economic development zone.

Binbo Biological Products Co. Ltd., is a professional high-tech enterprise which engaged in Biological products raw materials. Company was established in 2001, currently our company has more than 28 thousand square meters covering area. Factory buildings and workshops were establishsd by modern production requirements.There are three steps of development project which planned to invest around 60 million RMB. Currently the first step were finished and spent 28 million RMB, which met the production and office requirements.

Binbo is engaged in R&D with perfect equipments and advanced detecting instruments. The factory is in strict accordance with GMP standard in the course of design and construction.

 

 

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