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Levothyroxine Thyroxine T4
Product Name: | L-Thyroxine |
Synonyms: | 3,5,3’,5’-tetraiodothyronine;beta-[(3,5-diiodo-4-hydroxyphenoxy)-3,5-diiodophenyl]alanine;l-3,5,3’,5’-tetraiodothyronine;l-t4;o-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-l-tyrosin;o-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodotyrosine;t4(hormone);tetraiodothyronine |
CAS: | 51-48-9 |
MF: | C15H11I4NO4 |
MW: | 776.87 |
EINECS: | 200-101-1 |
Product Categories: | Amino Acids;Organics;Heterocyclic Compounds;Amino Acids & Derivatives;Intermediates & Fine Chemicals;Pharmaceuticals;Isotope Labeled Compounds;Aromatics;Isotope Labelled Compounds;SYNTHROID;Isolabel;Other APIs;Inhibitors |
Mol File: | 51-48-9.mol |
L-Thyroxine Chemical Properties |
Melting point | 235 °C |
alpha | -5 º (1N NaOH:EtOH 1:2) |
Fp | 9℃ |
storage temp. | 2-8°C |
solubility | Dissolves in 4M ammonium hydroxide in Methanol at 50mg/ml |
pka | 2.2(at 25℃) |
form | Powder |
color | White to Pale Brown |
Water Solubility | insoluble |
Sensitive | Light Sensitive |
Merck | 9491 |
InChIKey | XUIIKFGFIJCVMT-LBPRGKRZSA-N |
CAS DataBase Reference | 51-48-9(CAS DataBase Reference) |
EPA Substance Registry System | L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)- 3,5-diiodo-(51-48-9) |
Safety Information |
Hazard Codes | Xn,T,F |
Risk Statements | 40-39/23/24/25-23/24/25-11 |
Safety Statements | 22-24/25-36-45-36/37-16 |
RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution |
WGK Germany | 3 |
RTECS | YP2833500 |
F | 8-10 |
TSCA | Yes |
HazardClass | IRRITANT |
Hazardous Substances Data | 51-48-9(Hazardous Substances Data) |
MSDS Information |
Provider | Language |
---|---|
3,3',5,5'-Tetraiodo-L-thyronine | English |
SigmaAldrich | English |
ACROS | English |
L-Thyroxine Usage And Synthesis |
Chemical Properties | Crystalline Solid |
Uses | antihypercholesterimic, thyromimetic |
Uses | One of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroi d hormone, but has been used to treat hyperlipidemia. |
Definition | ChEBI: The L-enantiomer of thyroxine. |
Uses | antihypercholesterimic, thyromimetic |
Uses | One of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroi d hormone, but has been used to treat hyperlipidemia. |
Definition | ChEBI: The L-enantiomer of thyroxine. |
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Binbo Biological Products Co. Ltd., is a professional high-tech enterprise which engaged in Biological products raw materials. Company was established in 2001, currently our company has more than 28 thousand square meters covering area. Factory buildings and workshops were establishsd by modern production requirements.There are three steps of development project which planned to invest around 60 million RMB. Currently the first step were finished and spent 28 million RMB, which met the production and office requirements.
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