High Quality Drospi...

High Quality Drospirenone intermediate Q4 in stock fast delivery

High Quality Drospirenone intermediate Q4 in stock fast delivery

Min.Order / FOB Price:Get Latest Price

10 Gram

Negotiable

  • Min.Order :10 Gram
  • Purity: 99%
  • Payment Terms : T/T,

Keywords

Drospirenone intermediate Q4 CAS 82543-15-5

Quick Details

  • Appearance:white powder
  • Application:an ingredient in some birth control pills and hormone replacement therapy
  • PackAge:aluminum foil bag, discreet packing
  • ProductionCapacity:100|Kilogram|Month
  • Storage:cool and dry place
  • Transportation:EMS,DHL,HK post,EUB,ETK,NL post,Germany post

Superiority:

1.high quality:

quality is life. quality is the most important element for all goods. we have a lab doing research in wuhan china. hplc and nmr is available if needed.

2.reasonable price:

we provide high quality products with competitive price in china. all customers are welcomed to send us inquiries and get quotation.

3.low moq:

no worry about the low moq, our moq is 1 gram or even lower.

4.good service.

fast response. we promise to reply within 24 hours including holidays and send quotation sheet and other documents within 48 hours.

5. fast shipping and secure courier.

we promise to send out products and provide tracking number within 3 working days. and we send via different couriers based on different destination countries. we usually use nl post, hk post, germany post, eub, etk, etc.

 

 

Details:

 Introduction:

· Drospirenone is an ingredient in some birth control pills and hormone replacement therapy. In combination with ethinyl estradiol it is used ascontraception, and for women who want contraception it is also approved by the U.S. Food and Drug Administration (FDA) to treat moderate acne andpremenstrual dysphoric disorder.

· Drospirenone has anti-androgenic effects in addition, it also has the effect of salt corticosteroids, to prevent water and sodium retention in the body. Not only has excellent contraceptive effectiveness, but also on women's health has many positive effects. Such as to reduce acne and make skin more smooth and effective control of body weight.

 

· Function&usage:

· Drospirenone is taken orally with about 76% bioavailability. It is bound by other serum proteins. Metabolites have not been shown to be biologically active, show up in urine and feces, and are essentially completely excreted within 10 days.

·  The compound differs from other synthetic progestins in that its pharmacological profile in preclinical studies shows it to be closer to the natural progesterone. As such it has anti-mineralocorticoid properties, counteracts the estrogen-stimulated activity of the renin-angiotensin-aldosterone system, and is not androgenic. The anti-aldosterone properties exhibited by drospirenone promote sodium excretion and prevent water retention

 

·  Specification:

ITEMS

SPECIFICATIONS

RESULTS

Appearance

White or almost white crystalline powder

Conforms

Identification

IR, HPLC

Conforms

Melting point

198~203°C

199.3~201.9°C

Specific rotation

(10mg/ml methanol)

-186°to -196°

-190.5°

Heavy metals

NMT 20PPM

<20PPM

Water

NMT 0.2%

0.09%

Sulphated ash

NMT 0.1%

0.05%

Limit of 1,2-dimethoxyethane

Limit of isopropyl ether

NMT 0.2%

NMT 0.1%

UDL

0.02%

Related substances (HPLC)

Single impurity NMT 0.1%

Total impurities NMT 0.4%

0.07%

0.22%

Assay

98.0~101.0%

99.9%

Conclusion: It conforms to the USP32 STANDARD.

 

 

 

Packing and shipping

 

 

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