SNS-314 Mesylate ca...

SNS-314 Mesylate cas1146618-41-8

SNS-314 Mesylate cas1146618-41-8

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1 Kilogram

FOB Price: USD 1300.0000

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  • Purity: 99%
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SNS-314 1146618-41-8 SNS-314 Mesylate

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  • Appearance: powder or crystal
  • Application:SNS-314 Mesylate cas1146618-41-8
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  • ProductionCapacity:1000|Metric Ton|Month
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SNS-314 is a selective and potent pan Aurora inhibitor currently in a dose escalation phase 1 clinical trial for the treatment of patients with advanced solid tumors. SNS-314 has predominantly additive effects when administered concurrently with commonly used anticancer agents. Sequential administration of SNS-314 with chemotherapeutic compounds showed additive antiproliferative effects with carboplatin, gemcitabine, 5-FU, daunomycin, and SN-38, and synergy was observed in combination with gemcitabine, docetaxel, or vincristine.SNS-314 mesylate is capable to efficiently reduce cell growth and tumorigenicity of different ATC derived cell lines suggesting its potential therapeutic value for ATC treatment.

 

Name   N-(3-Chlorophenyl)-N'-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-2-thiazolyl]urea methanesulfonate (1:1)
copyRight
Molecular Structure   CAS # 1146618-41-8, N-(3-Chlorophenyl)-N'-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-2-thiazolyl]urea methanesulfonate (1:1)
 
Molecular Formula   C18H15ClN6OS2.CH4O3S
Molecular Weight   527.03
CAS Registry Number   1146618-41-8

 

Details:

 
Name   N-(3-Chlorophenyl)-N'-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-2-thiazolyl]urea methanesulfonate (1:1)
copyRight
Molecular Structure   CAS # 1146618-41-8, N-(3-Chlorophenyl)-N'-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-2-thiazolyl]urea methanesulfonate (1:1)
 
Molecular Formula   C18H15ClN6OS2.CH4O3S
Molecular Weight   527.03
CAS Registry Number   1146618-41-8
 
 
 
 
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Package: 1kg/Aluminum foil bag
Production Capacity: 500 Kilogram/Month
Appearance: white powder
 
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3-(1H-Imidazol-4-yl)pyridine
[CAS]

51746-85-1
[Synonyms]

3-(1H-IMIDAZOL-4-YL)PYRIDINE
4-(3-PYRIDYL)IMIDAZOLE
3-(1h-imidazol-4-yl)-pyridin
3-(4-Imidazolyl)Pyridine
3-(1H-Imidazol-4-yl)pyridine Discontinued See: I351751
4-(3-Pyridyl)imidazol
[Molecular Formula]

C8H7N3
[MDL Number]

MFCD01691712
[Molecular Weight]

145.16
[Appearance]

Light Yellow Solid
[mp ]

117-118°C
[Usage]

Imidazole rings are found in numberous natural compounds such as enzymes, nucleic acid, and alkaloids that play a role in biological processes
 

 

CAS: 451492-95-8
name MP-412
other name  MP-412;AV-412;AV-412 (free base);N-(4-((3-Chloro-4-fluorophenyl)amino)-7-(3-methyl-3-(4-methylpiperazin-1-yl)but-1-yn-1-yl)quin;N-(4-((3-chloro-4-fluorophenyl)amino)-7-(3-methyl-3-(4-methylpiperazin-1-yl)but-1-yn-1-yl)quinazolin-6-yl)acrylamide;N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-methyl-3-(4-methyl-1-piperazinyl)-1-butyn-1-yl]-6-quinazolinyl]-2-propenamide;2-PropenaMide, N-[4-[(3-chloro-4-fluorophenyl)aMino]-7-[3-Methyl-3-(4-Methyl-1-piperazinyl)-1-butyn-1-yl]-6-quinazolinyl]-
name: AV-412
CBNumber: CB52500949
mf C27H28ClFN6O
mw 507.02
 

 

Name

AT-9283

 EINECS  
CAS No. 896466-76-5   Density 1.45g/cm3
Solubility   Melting Point  
Formula C19H23N7O2 Boiling Point  
Molecular Weight 381.4316 Flash Point  
Transport Information   Appearance  
Safety   Risk Codes  
Molecular Structure Molecular Structure of 896466-76-5 (AT-9283) Hazard Symbols  
Synonyms

 
Name

AT-9283

 EINECS  
CAS No. 896466-76-5 Density 1.45g/cm3
Solubility   Melting Point  
Formula C19H23N7O2 Boiling Point  
Molecular Weight 381.4316 Flash Point  
Transport Information   Appearance  
Safety   Risk Codes  
Molecular Structure Molecular Structure of 896466-76-5 (AT-9283) Hazard Symbols  
Synonyms

 

Product Name: N-Methyl-N-[2-[[[2-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]-5-trifluoromethylpyrimidin-4-yl]amino]methyl]phenyl]methanesulfonamide
Synonyms: N-Methyl-N-[2-[[[2-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]-5-trifluoromethylpyrimidin-4-yl]amino]methyl]phenyl]methanesulfonamide;N-[2-[[[2-[(2,3-Dihydro-2-oxo-1H-indol-5-yl)aMino]-5-(trifluoroMethyl)-4-pyriMidinyl]aMino]Methyl]phenyl]-N-MethylMethanesulfonaMide;N-methyl-N-(2-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)phenyl)methanesulfonamide;N-Methyl-N-[2-[[[2-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]-5-trifluoromethylpyrimidin-4-yl]amino]methyl]phenyl]methanesulfonamide PF-431396;N-[2-[[[2-[(2,3-dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]phenyl]-N-methyl-Methanesulfonamide hydrate;PF-431396 hydrate;PF 431396, >=98%;N-Methyl-N-(2-(((2-((2-oxoindolin-5-yl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)methyl)p
CAS: 717906-29-1
MF: C22H21F3N6O3S
MW: 506.5

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