Anastrozole of API ...

Anastrozole of API CAS 120511-73-1

Anastrozole of API CAS 120511-73-1

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1 Kilogram

FOB Price: USD 1300.0000

  • Min.Order :1 Kilogram
  • Purity: 99%
  • Payment Terms : L/C,T/T,

Keywords

Anastrozole 120511-73-1 Anastrozole supplier

Quick Details

  • Appearance: powder or crystal
  • Application: Anastrozole of API CAS 120511-73-1
  • PackAge:Aluminum Foil Bag or as your requirement
  • ProductionCapacity:1000|Metric Ton|Month
  • Storage:keep in dry place
  • Transportation:as your requirement

Superiority:

 

We do following terms :

1) Best quality 

2) Many years experience in this field

3) Loyal customers in countries

4) Professional big supplier

5) Safe shipping

6) Various payment terms

 

Anastrozole, sold under the trade name Arimidex among others, is a medication used in addition to other treatments for breast cancer. Specifically it is used for hormone receptor-positive breast cancer. It has also been used to prevent breast cancer in those at high risk. It is taken by mouth

Details:

 

Product Introduction 

 

1.Product name: Anastrozole


2.Synonym: Tetramethyl-5-(1H-1,2,4-triazol-1ylmethyl) 1,3-benzenediacetionitrile

 

Assay99%


3.Molecular formulaC17H19N5


4.Molecular weight 293.37


5.Appearancewhite crystal powder


6.CAS number120511-73-1


7.Medicinal categoriesnon-steroidal aromatase inhibitors

 

 

Items

Standard

Results

Description

White crystalline powder

Complies

Identification

IR

HPLC

Reactive

Conform with standard IR

Conform with standard HPLC

Conform

Solubility

Freely soluble in methanol,acetone,ethanol and tetrahydrofuran.And very soluble in acetonitrile

Complies

Total Impurity

max.0.5%

0.18%

Total Unspecified Impurity

max. 0.2%

0.08%

Individual unspecified impurlty

max. 0.1%

0.05%

Related compound B

max. 0.2%

0.07%

Related compound C

max. 0.2%

0.04%

Related compound D

max. 0.1%

0.05%

Related compound E

max. 0.1%

0.06%

Limit of cyclohexane

max. 0.08%

ND

Limit of ethylacetate

max. 0.1%

0.07%

Melting point

81.0~84.0°C

82.5~83.2°C

Water

max. 0.3%

0.21%

Residue on ignition

max. 0.1%

0.07%

Heavy Metals

max.0.001%

Complies

Assay(HPLC)

98.0%~102.0%

99.8%

Storage

Cool and dry

Conclusion

It complies to USP32 .

 

Anastrozole is an inhibitor for the triazole aromatase with a strong selectivity. It can inhibits aromatase which is prerequisite for the synthesis of pigment cells P-450 thereby blocking the biosynthesis of estrogens, and the estrogen is the essential part of the growth of breast cancer cells. The 50% inhibitory concentration (IC50) value of anastrozole to placental aromatase is 15nmol/L.


Anastrozole dosage:
You take anastrozole as a tablet, once a day. Try to take it at the same time each day. Swallow the tablet whole with a drink of water. You can take it before, with, or after food.
It is very important that you take tablets according to the instructions your doctor or pharmacist gives you. You should take the right dose, not more or less. It is a long term treatment and you usually need to take it for several years. Never stop taking a cancer drug without talking to your specialist first.
If you accidentally take more anastrozole than you should, let your doctor know straight away. 
If you forget a dose, continue with the next dose as normal. Don't take an extra dose to make up for the missed one.

Anastrozole Uses:
 (1) It is the third-generation’s aromatase inhibitors, used for the treatment of advanced breast cancer of postmenopausal patients.
(2) Its used to cure the breast cancer.
(3) Anastrozole is the third-generation’s aromatase inhibitors, used for the treatment of advanced breast cancer of postmenopausal patients. It is an inhibitor for the triazole aromatase with a strong selectivity. It can inhibits aromatase which is prerequisite for the synthesis of pigment cells P-450 thereby blocking the biosynthesis of estrogens, and the estrogen is the essential part of the growth of breast cancer cells. Its used to cure the breast cancer, particularly suitable for postmenopausal women with advanced breast cancer who recrudescent after hormone adjuvant therapy.
 
Packaging & Delivery
P     Packaging Details
25kg carton drum (32cm*58cm)or 1kg foil bag (10cm*15cm) or by request of clients
       Delivery Time
Shipped in 3 days after payment

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product advantage
1.our product are of high quality. the purity of hex is above 99.5%.
2.our product have reasonable prices. the more you buy , the lower the price will be.
3.the product will be sent out within 24 hours after getting payment and it will take 4-7 days to arrive your door.
4.our company is a leading professional manufacturer of apis and intermediate product
 
we are  biological technology co.,limited , our company are professional engaged in supplying and exporting many kinds of organic intermedicates products,pharmaceutical intermedicates,research chemicals and raw materials chemicals etc.
i hope you back to me and let me know what chemicals will you need and like , i like to offer you our best price and good quality as your reference .we will choose safe shipping way for you .
Package: 1kg/Aluminum foil bag
Production Capacity: 500 Kilogram/Month
Appearance: white powder
 
Packaging & Shipping

6.jpg

Packaging Details:

25kgs packaging Fiber drum outside and plastic bag inside 1-25kgs packaging aluminium bag outside and double plastic bag inside

Delivery Detail: within 3 days when get the payment.

 Shipping :
We have Professional shipping agent, based on customers ' demand for transport
By express :FEDEX,DHL,EMS ,UPS,TNT ect.
By SEA and By AIR

 

5.jpg

 

 

英文名称: N1-BENZYL-N1-ETHYL-PROPANE-1,3-DIAMINE
英文同义词: N1-BENZYL-N1-ETHYL-PROPANE-1,3-DIAMINE;TIMTEC-BB SBB010879;N-(3-aminopropyl)-N-benzyl-N-ethylamine;ASINEX-REAG BAS 03363498
CAS号: 140134-63-0
分子式: C12H20N2
分子量: 192.3
 

 

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