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Anastrozole 120511-73-1 Anastrozole supplier
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Anastrozole, sold under the trade name Arimidex among others, is a medication used in addition to other treatments for breast cancer. Specifically it is used for hormone receptor-positive breast cancer. It has also been used to prevent breast cancer in those at high risk. It is taken by mouth
Product Introduction
1.Product name: Anastrozole
2.Synonym: Tetramethyl-5-(1H-1,2,4-triazol-1ylmethyl) 1,3-benzenediacetionitrile
Assay99%
3.Molecular formulaC17H19N5
4.Molecular weight 293.37
5.Appearancewhite crystal powder
6.CAS number120511-73-1
7.Medicinal categoriesnon-steroidal aromatase inhibitors
Items |
Standard |
Results |
Description |
White crystalline powder |
Complies |
Identification |
IR HPLC Reactive |
Conform with standard IR Conform with standard HPLC Conform |
Solubility |
Freely soluble in methanol,acetone,ethanol and tetrahydrofuran.And very soluble in acetonitrile |
Complies |
Total Impurity |
max.0.5% |
0.18% |
Total Unspecified Impurity |
max. 0.2% |
0.08% |
Individual unspecified impurlty |
max. 0.1% |
0.05% |
Related compound B |
max. 0.2% |
0.07% |
Related compound C |
max. 0.2% |
0.04% |
Related compound D |
max. 0.1% |
0.05% |
Related compound E |
max. 0.1% |
0.06% |
Limit of cyclohexane |
max. 0.08% |
ND |
Limit of ethylacetate |
max. 0.1% |
0.07% |
Melting point |
81.0~84.0°C |
82.5~83.2°C |
Water |
max. 0.3% |
0.21% |
Residue on ignition |
max. 0.1% |
0.07% |
Heavy Metals |
max.0.001% |
Complies |
Assay(HPLC) |
98.0%~102.0% |
99.8% |
Storage |
Cool and dry |
|
Conclusion |
It complies to USP32 . |
Anastrozole is an inhibitor for the triazole aromatase with a strong selectivity. It can inhibits aromatase which is prerequisite for the synthesis of pigment cells P-450 thereby blocking the biosynthesis of estrogens, and the estrogen is the essential part of the growth of breast cancer cells. The 50% inhibitory concentration (IC50) value of anastrozole to placental aromatase is 15nmol/L.
Packaging Details:
25kgs packaging Fiber drum outside and plastic bag inside 1-25kgs packaging aluminium bag outside and double plastic bag inside
Delivery Detail: within 3 days when get the payment.
Shipping :
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英文名称: | N1-BENZYL-N1-ETHYL-PROPANE-1,3-DIAMINE |
英文同义词: | |
CAS号: | 140134-63-0 |
分子式: | C12H20N2 |
分子量: |
192.3 |
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