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Losartan potassium 124750-99-8 Losartan potassium supplier
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Product Name: | Losartan potassium |
Synonyms: | 2-BUTYL-4-CHLORO-1-[[2'-(1H-TETRAZOL-5YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1H-IMIDAZOLE-5-METHANOL;2-butyl-4-chloro-1-[[2'-(1h-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1h-imidazole-5-methanol monopotassium salt;2-BUTYL-4-CHLORO-1-[[2'-(1H-TETRAZOLE-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1H-IMIDAZOLE-5-METHANOL, POTASSIUM SALT;COZAAR;DUP 753;LOSARTAN MONOPOTASSIUM SALT;LOSARTAN POTASSIUM;LOSARTAN POTASSIUM SALT |
CAS: | 124750-99-8 |
MF: | C22H23ClKN6O |
MW: | 462.01 |
EINECS: | 200-287-4 |
As a angiotensin II receptor antagonist, Losartan Potassium is the potassium salt of losartan with antihypertensive activity, which is mainly used in the therapy of high blood pressure (hypertension) and diabetic nephropathy. It functions by relaxing blood vessels so that blood can flow more easily. It is also effective to help protect the kidneys from damage caused by diabetes and lower the risks of stroke in patients suffering from hypertension and myocardial enlargement. Besides, recent study has suggested that losartan is beneficial to reverse age related dysfunction in maintaining normal blood pressure and cellular energy usage on mitochondria and it can probably be used to treat left ventricular hypertrophy. It may also be used as an alternative agent for the treatment of systolic dysfunction, myocardial infarction, coronary artery disease, and heart failure.
Item |
Standards |
Results |
Characters |
White or almost white crystalline powder |
White crystalline powder |
Identification |
Infrared absorption: Must similar to reference standard |
Conforms |
Ultraviolet absorption: Must similar to reference standard |
Conforms |
|
Test for potassium: Must be positive |
Positive |
|
Water |
NMT 0.5% |
0.1% |
Heavy metals |
NMT 0.001% |
Conforms |
Chromatographic purity |
Any individual impurity NMT 0.2% |
0.01% |
Total impurities NMT 0.5% |
0.04% |
|
Residual solvents |
Cyclohexane NMT 0.1% |
0.007% |
Isopropyl alcohol NMT 0.2% |
0.03% |
|
Assay(HPLC) |
98.5~101.0% |
99.2% |
Packaging Details:
25kgs packaging Fiber drum outside and plastic bag inside 1-25kgs packaging aluminium bag outside and double plastic bag inside
Delivery Detail: within 3 days when get the payment.
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