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Spironolactone 52-01-7 Spironolactone supplier
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Product Name: | Spironolactone |
Synonyms: | ,(7alpha,17alpha)-;17alpha-Pregn-4-ene-21-carboxylic acid, 17-hydroxy-7alpha-mercapto-3-oxo-, gamma-lactone, acetate;17-alpha-Pregn-4-ene-21-carboxylic acid, 1-hydroxy-7-alpha-mercapto-3-oxo-alpha-lactone;17-alpha-pregn-4-ene-21-carboxylicacid,1-hydroxy-7-alpha-mercapto-3-oxo-alpha;17-Hydroxy-7alpha-mercapto-3-oxo-17alpha-pregn-4-ene-21-carboxylic acid gamma-lactone acetate;17-hydroxy-7-alpha-mercapto-3-oxo-17-alpha-pregn-4-ene-21-carboxylicaciga;17-hydroxy-7alpha-mercapto-3-oxo-17alpha-pregn-4-ene-21-carboxylicacigamm;3-(3-keto-7-alpha-acetylthio-17-beta-hydroxy-4-androsten-17-alpha-yl)propion |
CAS: | 52-01-7 |
MF: | C24H32O4S |
MW: | 416.57 |
EINECS: | 200-133-6 |
Product Categories: | Active Pharmaceutical Ingredients;Biochemistry;Steroids;Steroids (Others);Intermediates & Fine Chemicals;Pharmaceuticals;API's;ALDACTONE |
Mol File: | 52-01-7.mol |
ITEMS | STANDARDS | RESULTS |
Appearance (Ph.Eur.) | A white or yellowish-white powder | White powder |
Solubility (Ph.Eur.) | Practically insoluble in water, soluble in ethanol (96%) | Complies |
Identification | ||
A. IR –spectrum (Ph.Eur.) | Meet the requirement | Complies |
A. IR –spectrum (USP) | Meet the requirement | Complies |
B. TLC (Ph.Eur.) | Meet the requirement | Complies |
B. UV absorption (USP) | Meet the requirement | Complies |
C. Colour reaction (Ph.Eur.) | Meet the requirement | Complies |
C. Precipitate reaction (USP) | Meet the requirement | Complies |
Specific optical rotation | -41°~-46° | -42.8° |
(Ph.Eur.) | -41°~-45° | -42.9° |
(USP) | ||
Sulphated ash (Ph.Eur.) | ≤0.1% | 0.00% |
Related substances (Ph.Eur.) | ||
Impurity A | ≤0.2% | N.D. |
Impurity B | ≤0.3% | N.D. |
Impurity C | ≤0.2% | N.D. |
Impurity D | ≤0.15% | N.D. |
Impurity E | ≤0.3% | N.D. |
Impurity I | ≤0.5% | 0.05% |
Any unspecified impurity | ≤0.10% | Complies |
Total | ≤0.7% | 0.13% |
Ordinary impurities (USP) | ≤2.0% | Complies |
Free thiol compounds (Ph.Eur.) | ≤0.05mL | Complies |
Free mercapto compounds (USP) | ≤0.10mL | Complies |
Chromium (Ph.Eur.) | ≤50ppm | Complies |
Assay | 97.5%~102.0% | 100.90% |
HPLC (Ph.Eur.) | 97.5%~103.0% | 99.60% |
HPLC (USP) | ||
Residual solvent (In-house) | ≤3000ppm | 90ppm |
Methanol | ≤720ppm | ≤LOD (0.0046ppm) |
Tetrahydrofuran | ≤880ppm | ≤LOD (0.23ppm) |
DMF | ||
Particle size (In-house) | 95% ≤ 20 microns | Complies |
Conclusion | Compiles with EP7/USP35 |
1) As a diuretic, antihypertensive, Spironolactone is used primarily to treat heart failure, axcites in patients with
liver disease, low-renin hypertension, hypokalemia
2) As an antiandrogen. Spironolactone is a potent antagonst of the androgen receptor as well as an inhibitor of
androgen production.
3) As cosmetic, Spironolactone have an effect in hair grow.
Packaging Details:
25kgs packaging Fiber drum outside and plastic bag inside 1-25kgs packaging aluminium bag outside and double plastic bag inside
Delivery Detail: within 3 days when get the payment.
Shipping :
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By SEA and By AIR
Product Name: | Polyethylene-polypropylene glycol |
Synonyms: | BLOCK COPOLYMER OF POLYETHYLENE AND POLYPROPYLENE GLYCOL;SYNPERONIC F 108;SYNPERONIC L 121;SYNPERONIC L 122;SYNPERONIC P 105;SYNPERONIC P 85;SYNPERONIC PE(R)/F68;SYNPERONIC PE(R)/L61 |
CAS: | 9003-11-6 |
MF: | C5H10O2 |
MW: | 0 |
EINECS: |
618-355-0 |
Product Name: | Lamivudine |
Synonyms: | LaMivudine(Epivir);4-AMino-1-[(2R,5S)-2-(hydroxyMethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyriMidinone;3TC (-)-1-[(2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine;3TC/Epivir-HBV;4-AMino-1-((2R,5S)-2-(hydroxyMethyl)-1,3-oxathiolan-5-yl)pyriMidin-2(1H)-one;LaMivudine-13C-d2;cis-Lamivudine;(-)-BCH-189 |
CAS: | 134678-17-4 |
MF: | C8H11N3O3S |
MW: | 229.26 |
Product Categories: | API;DENDRID;Piperazines;Active Pharmaceutical Ingredients;Antivirals for Research and Experimental Use;Biochemistry;Chemical Reagents for Pharmacology Research;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents;Anti-virals;Intermediates & Fine Chemicals;Pharmaceuticals;API's;HIV/AIDS/Related Products;Sulfur & Selenium Compounds |
Mol File: |
134678-17-4.mol |
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