CasNo.63775-96-2,63775-96-2 CYCLOSPORIN D C63H111N11O12,(63775-96-2) Suppliers

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Purity: 99.5%
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CYCLOSPORIN D 63775-96-2 C63H111N11O12

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Appearance:Powder
Application:63775-96-2
PackAge:Aluminium Foil Bag and Paper Drum
ProductionCapacity:1|Metric Ton|Day
Storage:1MT
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Details:

CYCLOSPORIN D Basic information

Product Name:	CYCLOSPORIN D
Synonyms:	CYCLOSPORIN D;Val2-cyclosporine;(3R,4R)-3-Hydroxy-N-methyl-5-[(E)-1-propenyl]-cyclo(L-Leu-L-Val-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-);(3R,4R)-3-Hydroxy-N-methyl-5-[(E)-1-propenyl]cyclo(L-Leu-L-Val-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-);Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-valyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl];7-L-Valinecyclosporin A;Cyclosporine IMpurity-D;7-L-valinecyclosporine A
CAS:	63775-96-2
MF:	C63H111N11O12
MW:	1214.62
EINECS:	200-835-2
Product Categories:	ACTIVE PHARMACEUTICAL INGREDIENTS;Intermediates & Fine Chemicals;Peptides;Pharmaceuticals;Anti-cancer&immunity
Mol File:	63775-96-2.mol

CYCLOSPORIN D Chemical Properties

Melting point	148-1510C
alpha	D20 -245° (c = 0.52 in CHCl3); D20 -211° (c = 0.51 in methanol)
Fp	9 °C
storage temp.	-20°C Freezer

Safety Information

Hazard Codes	F,Xn,T
Risk Statements	11-20/21/22-36-39/23/24/25-23/24/25
Safety Statements	16-36/37-45-7
RIDADR	UN 1648 3 / PGII

MSDS Information

CYCLOSPORIN D Usage And Synthesis

Chemical Properties	Colorless Crystalline Solid
Uses	A group of nonpolar cyclic oligopeptides with immunosupppressant activity.
Uses	Cyclosporin D is a minor analogue of the cyclosporin family which is only weakly immunologically active. Cyclosporin D is a potent inhibitor of tumour-promoting phorbol esters on mouse skin in vivo, and a potent inhibitor of calcium/calmodulin-dependent EF-2 phosphorylation in vitro.
Uses	Cyclosporin D is a minor analogue of the cyclosporin family which is only weakly immunologically active. Cyclosporin D is a potent inhibitor of tumor-promoting phorbol esters on mouse skin in vivo, and a potent inhibitor of calcium/calmodulin-dependent EF-2 phosphorylation in vitro.