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Ciprofloxacin 85721-33-1 Ciprofloxacin supplier
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CAS Number:86393-32-0
Name:Ciprofloxacin hydrochloride hydrate
Formula:C17H18FN3O3.ClH.H2O
Molecular Weight:385.82
Synonyms:3-Quinolinecarboxylicacid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-,monohydrochloride, monohydrate (9CI);Ciprofloxacin hydrochloride monohydrate;Ciprofloxacin Monohydrochloridecas;Ciprofloxacin Monohydrochloride;Ciprofloxacin hydrochloride;Ciprofloxaicin HCl;3-Quinolinecarboxylicacid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-,hydrochloride, hydrate (1:1:1);
Melting Point:318-320 °C
Boiling Point:581.8 °C at 760 mmHg
Flash Point:305.6 °C
Appearance:White or yellowish crystalline powder
Tests |
Acceptance Criteria |
Test Result |
Description |
Off-white to light yellowish free flowing products |
Conforms |
Identification
|
The retention time of principle peak in the chromatogram of the substance to be examined corresponds to that in the chromatogram of the reference substance |
Conforms |
Moisture content by Karl ficher |
2.5-6.5% |
6.2% |
Bulk density Untapped |
0.35-0.55g/ml |
0.43g/ml |
Bulk density tapped |
0.55-0.75g/ml |
0.49g/ml |
Related substance |
Any other individual impurity ≤0.1% Total impurities ≤0.5% |
0.09% 0.4% |
Ciprofloxacin Content (On anhydrous basis) |
72.0-79.5% |
75.5% |
Dissolution |
≥80%(after 30minutes) |
89.0% |
Microbiology |
Bacterial count ≤1000CFU/mg Fungal count ≤100CFU/mg Escherichia coli: absent Salmonella spp:absent Pesudomonas aeruginosa:absent |
/ / / / / |
Sieve Analysia ASTM Mesh No. The US Std.sieve #40 The US Std.sieve #100 |
%Cumulative retention 10-55% Not less than 55% |
78.6% 91.8% |
Conclusion: The product conforms to the above specifications. |
USE: pharmaceutical raw material
Ciprofloxacin HCl drug is used for the treatment of Bacterial infection of Respiratory tract, UTI, Uncomplicated Cystitis in females, GI, Chronic Bacterial Prostatitis, CNS, Immuno compromised patients, Skin, Bone and Joint Infections, Uncomplicated cervical and urethral gonorrhea.
Ciprofloxacin HCl drug has in vitro activity against a wide range of gram-negative and gram-positive organisms.
Ciprofloxacin HCl drug inhibits bacterial DNA gyrase, an enzyme responsible for counteracting excessive supercoiling of DNA during replication or transcription. The mechanism of action of quinolones, including
Ciprofloxacin HCl drug, is different from that of other antimicrobial agents such as beta-lactams, macrolides, tetracyclines, or aminoglycosides; therefore, organisms resistant to these drugs may be susceptible to Ciprofloxacin HCl drug. There is no known cross-resistance between ciprofloxacin HCl drug and other classes of antimicrobials.
Packaging Details:
25kgs packaging Fiber drum outside and plastic bag inside 1-25kgs packaging aluminium bag outside and double plastic bag inside
Delivery Detail: within 3 days when get the payment.
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Product Name: | Polyethylene-polypropylene glycol |
Synonyms: | BLOCK COPOLYMER OF POLYETHYLENE AND POLYPROPYLENE GLYCOL;SYNPERONIC F 108;SYNPERONIC L 121;SYNPERONIC L 122;SYNPERONIC P 105;SYNPERONIC P 85;SYNPERONIC PE(R)/F68;SYNPERONIC PE(R)/L61 |
CAS: | 9003-11-6 |
MF: | C5H10O2 |
MW: | 0 |
EINECS: |
618-355-0 |
Product Name: | Lamivudine |
Synonyms: | LaMivudine(Epivir);4-AMino-1-[(2R,5S)-2-(hydroxyMethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyriMidinone;3TC (-)-1-[(2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine;3TC/Epivir-HBV;4-AMino-1-((2R,5S)-2-(hydroxyMethyl)-1,3-oxathiolan-5-yl)pyriMidin-2(1H)-one;LaMivudine-13C-d2;cis-Lamivudine;(-)-BCH-189 |
CAS: | 134678-17-4 |
MF: | C8H11N3O3S |
MW: | 229.26 |
Product Categories: | API;DENDRID;Piperazines;Active Pharmaceutical Ingredients;Antivirals for Research and Experimental Use;Biochemistry;Chemical Reagents for Pharmacology Research;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents;Anti-virals;Intermediates & Fine Chemicals;Pharmaceuticals;API's;HIV/AIDS/Related Products;Sulfur & Selenium Compounds |
Mol File: |
134678-17-4.mol |
Product Name | Metroprolol succinate |
Appearance | white powder |
CAS | 98418-47-4 |
Grade | Medicine & Food |
Other Name | Metroprolol succi |
Assay | 99%min |
Shelf life | 2 Years |
Standard | USP30 |
Application | Pharmaceutical Raw Intermediates |
Color | white |
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