142273-20-9 KENPAUL...

142273-20-9 KENPAULLONE C16H11BrN2O
142273-20-9 KENPAULLONE C16H11BrN2O
142273-20-9 KENPAULLONE C16H11BrN2O
142273-20-9 KENPAULLONE C16H11BrN2O
142273-20-9 KENPAULLONE C16H11BrN2O

142273-20-9 KENPAULLONE C16H11BrN2O

Min.Order / FOB Price:Get Latest Price

1 Metric Ton

Negotiable

  • Min.Order :1 Metric Ton
  • Purity: 99%
  • Payment Terms : L/C,D/A,D/P,T/T,

Keywords

KENPAULLONE 142273-20-9 C16H11BrN2O

Quick Details

  • Appearance:white powder
  • Application:Organic Chemicals
  • PackAge:based on the bulk quantity
  • ProductionCapacity:|Metric Ton|Day
  • Storage:RT
  • Transportation:based on the order quantity

Superiority:

KENPAULLONE Basic information
Product Name: KENPAULLONE
Synonyms: 9-BROMO-7,12-DIHYDRO-INDOLO[3,2-D][1]BENZAZEPIN-6(5H)-ONE;8-BROMO-7,12-DIHYDRO-INDOLO[3,2-D][1]-BENZAZEPIN-6(5H)-ONE;KENPAULLONE;NSC-664704;9-Bromo-7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one, NSC 664704;9-bromo-7,12-dihydro-5H-indolo[3,2-d][1]benzazepin-6-one;9-BroMopaullone;Kenpaullon
CAS: 142273-20-9
MF: C16H11BrN2O
MW: 327.18
EINECS:
Product Categories: All Inhibitors;Inhibitors;Protein Kinase;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File: 142273-20-9.mol
KENPAULLONE Structure
KENPAULLONE Chemical Properties
Melting point >300°C (dec.)
storage temp. 2-8°C
solubility DMSO: 18 mg/mL, clear, yellow
color yellow
InChIKey QQUXFYAWXPMDOE-UHFFFAOYSA-N
CAS DataBase Reference 142273-20-9(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
KENPAULLONE Usage And Synthesis
Chemical Properties Tan Solid
Uses The paullones are a novel class of kinase inhibitors, initially identified as CDK inhibitors. Kenpaullone has been found to be a useful GSK-3 inhibitor (IC50=23nM).
Biological Activity Potent inhibitor of CDK1/cyclin B and GSK-3 β (IC 50 values are 0.4 and 0.23 μ M respectively). Also inhibits CDK2/cyclin A, CDK2/cyclin E and CDK5/cyclin/p35 (IC 50 values are 0.68, 7.5 and 0.85 μ M respectively). Selective over c-src (IC 50 = 15 μ M), casein kinase 2 (IC 50 = 20 μ M), ERK1 (IC 50 = 20 μ M), ERK2 (IC 50 = 9 μ M) and a range of other protein kinases (IC 50 values > 35 μ M). Generates induced pluripotent stem cells (iPSCs) from somatic cells when used in combination with reprogramming factors; can replace Klf4.
 

Details:

our company was built in 2009 with an iso certificate.in the past 5 years, we have grown up as a famous fine chemicals supplier in china

and we had established stable business relationships with samsung,lg,merck,thermo fisher scientific and so on.


our advantage:

1.higest quality and good package 
2.fast delivery 
3.better payment term 
4.fast response to customer within 6 hours 
5.good business credit in europe ,us ,japan ,korea

View All
Visit Store

You Might Also Like

Related Searches

Contact Supplier

Confirm to collect the product to my collection?

OKCancel

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View