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We have been providing over 1000 products including molecular targeted anticancer drugs, cell signaling pathway
inhibitors, pharmaceutical intermediates, and heterocyclic compounds, and quality services including custom
synthesis, transfer of new drug patent and technology, technical cooperation, and process optimization.
Jinan Trio PharmaTech was founded by a core group of top overseas pharmaceutical chemists, Medical scientists and
business management experts, and is an enterprise of science and technology supported by the "Attracting High-
Level Talent Scheme" of Jinan government.
Jinan Trio PharmaTech Co., Ltd.
Year Establishment: 2008
Location: We are located at one of the largest National Technical Integrated Drug Discovery Platforms in the High-Tech Zone of Jinan City
Our company was founded by a core group of top overseas pharmaceutical chemists, medical scientists business
management experts
We have built up solid cooperation with over twenty oversea companies over one hundred domestic companies
since the foundation
Specifications:
Name Dovitinib
Synonyms 4-Amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one
Molecular Formula C21H21FN6O
Molecular Weight 392.44
CAS Registry Number 405169-16-6 (804551-71-1)
Applications:
Dovitinib (TKI258, CHIR258) is a novel multi-target inhibitor for Flt3, c-Kit, FGFR1/3, VEGFR1/2/3, PDGFRα/β with
IC50 of 1 nM, 2 nM, 8 nM/9 nM and 10 nM/13 nM/8 nM, 210 nM/27 nM respectively.
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