PP121

Details:

<p> <strong><strong>Year Establishment: 2008</strong></strong></p> <p> <strong><strong> </strong></strong></p> <p> <strong><strong>Location: At one of the largest National Technical Integrated Drug Discovery Platforms in the High-Tech Zone of Jinan City</strong></strong></p> <p>  </p> <p> <strong>Our company was founded by a core group of top overseas pharmaceutical chemists, medical scientists business </strong></p> <p> <strong>management experts</strong></p> <p>  </p> <p> <span style="font-family: times new roman"><font color="#282828" size="3">We have built up solid cooperation with over twenty oversea companies over one hundred domestic companies</font></span></p> <p> <span style="font-family: times new roman"><font color="#282828" size="3">since the foundation</font></span></p> <p>  </p> <p>  </p> <p>  </p> <p> <img alt="" src="http://www.lookchem.com/productdetail/day_131128/201311280335208799.jpg" style="width: 433px; height: 244px" /></p> <p>  </p> <p>  </p> <p>  </p> <p>  </p> <p>  </p> <p> <span style="color: #008000"><span style="font-size: 16px"><strong>Specifications:</strong></span></span></p> <p>  </p> <p>  </p> <p> Name  PP 121</p> <p>  </p> <p> <br /> Synonyms  1-Cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine</p> <p>  </p> <p> <br /> Molecular Formula  C₁₇H₁₇N₇</p> <p>  </p> <p> <br /> Molecular Weight  319.36</p> <p>  </p> <p> <br /> CAS Registry Number  1092788-83-4</p> <p> <br /> <br />  </p> <p> <span style="font-size: 16px"><strong><span style="color: #008000">Applications:</span></strong></span></p> <p>  </p> <p> PP-121 is a multi-target inhibitof PDGFR, Hck, mTOR, VEGFR2, Src Abl with IC50 of 2 nM, 8 nM, 10 nM, 12 nM, 14 nM 18 nM, respectively, also inhibits DNA-PK with IC50 of 60 nM.</p> <p>  </p> <p>  </p> <p>  </p> <p>  </p> <p> <img alt="" src="http://www.lookchem.com/productdetail/day_131128/201311280336047229.jpg" style="width: 438px; height: 286px" /></p> <p>  </p> <p>  </p> <p>  </p> <p>  </p> <p> <img alt="" src="http://www.lookchem.com/productdetail/day_131128/201311280336427578.jpg" style="width: 440px; height: 299px" /></p> <p>  </p> <p>  </p> <p>  </p> <p>  </p> <p> <img alt="" src="http://www.lookchem.com/productdetail/day_131205/20131205103909435.jpg" style="width: 443px; height: 244px" /></p> <p>  </p> <p>  </p> <p>  </p> <p>  </p> <p>  </p> <p>  </p>