Manufacturer high quality Cabazitaxel with best price 183133-96-2

Details:

 

    Product Description

                                               

Cabazitaxel	CAS 183133-96-2	Brand:sigma
	MW: 835.93	MSDS: Avaiable
	MF :C45H57NO14	Sample: Avaiable
	Category: Oncology drug	Min order: 1grams
	Quality standard Enterprise standard	Place of Origin:China
Appearance	White   powder
Introduction	is a semi-synthetic derivative of a natural taxoid.It was developed by Sanofi-Aventis and was approved by the U.S. Food and Drug Administration (FDA) for the treatment of hormone-refractory prostate cancer on June 17, 2010. It is a microtubule inhibitor, and the fourth taxane to be approved as a cancer therapy.
Applications	Pharmaceutical raw materials , Oncology drug

 

   Certification of Analysis

 

 

TEST ITEM		SPECIFICATION
Appearance		White or almost white crystalline powder
Identification		FT-IR
		HPLC
Water		3.0%
Melting Point		148°C­—158°C
Residue on Ignition		≤0.1%
Heavy metals		≤ 20ppm
Residual  Solvents	Acetone	≤ 5000ppm
	Dichloromethane	≤ 600ppm
	n-Hexane	≤ 290ppm
	Acetic acid	≤ 5000ppm
	Ethyl acetate	≤ 5000ppm
	Tetrahydrofuran	≤ 720ppm
	Ethanol	≤ 5000ppm
Related substances	cabazitaxel	≤ 0.3%
	10-DABIII	≤ 0.3%
	Any other single impurity	≤ 0.1%
	Total impurities	≤ 1.0%
Chromatographic purity(By HPLC)		≥99.0%

 

                          Function&Application

 

 

Cabazitaxel (previously XRP-6258) is a semi-synthetic derivative of a natural taxoid. It was developed by Sanofi-Aventis and was approved by the U.S. FDA for the treatment of hormone-refractory prostate cancer on June 17, 2010. It is a microtubule inhibitor, and the fourth taxane to be approved as a cancer therapy.

Cabazitaxel in combination with prednisone is a treatment option for hormone-refractory prostate cancer following docetaxel-based treatment.

 

 Cabazitaxel anticancer mechanism and characteristics similar with docetaxel, belongs to anti-microtubule drugs. Cabazitaxel through binding to tubulin, promoting their assembly into microtubules, and can prevent these have assembled a microtubule disintegration of the stabilization of microtubules, thereby inhibiting cell mitosis, and interphase cellular functions (interphasecellularfunctions) of play.

 

 

 

 

 

 

product advantage

1.our product are of high quality. the purity of hex is above 99.5%.

2.our product have reasonable prices. the more you buy , the lower the price will be.

3.the product will be sent out within 24 hours after getting payment and it will take 4-7 days to arrive your door.

4.our company is a leading professional manufacturer of apis and intermediate product

 

we are  biological technology co.,limited , our company are professional engaged in supplying and exporting many kinds of organic intermedicates products,pharmaceutical intermedicates,research chemicals and raw materials chemicals etc.

i hope you back to me and let me know what chemicals will you need and like , i like to offer you our best price and good quality as your reference .we will choose safe shipping way for you .

Package: 1kg/Aluminum foil bag

Production Capacity: 500 Kilogram/Month

Appearance: white powder

 

Packaging & Shipping

Packaging Details:

25kgs packaging Fiber drum outside and plastic bag inside 1-25kgs packaging aluminium bag outside and double plastic bag inside

Delivery Detail: within 3 days when get the payment.

 Shipping :
We have Professional shipping agent, based on customers ' demand for transport
By express :FEDEX,DHL,EMS ,UPS,TNT ect.
By SEA and By AIR

 

 

What is Kojic Acid

   Kojic acid is a chelation agent produced by several species of fungi, especially Aspergillus oryzae, which has the Japanese common name koji.Kojic acid is a by-product in the fermentation process of malting rice, for use in the manufacturing of sake, the Japanese rice wine. It is a mild inhibitor of the formation of pigment in plant and animal tissues, and is used in food and cosmetics to preserve or change colors of substances. It forms a bright red complex with ferric ions.

Applications:

♦.Kojic acid can reduces age spots and pigmentation on face and body, typically caused by sun damage. 
♦. It can eliminate free radicals, strengthen cell activity.
♦. Kojic acid is also known to have an anti-microbial effect.
♦. Non-toxic to person and livestock, pollution-free pesticide in insecticide production.

Product Name: Hyaluronic Acid 

What is Hyaluronic acid 

Hyaluronic acid(HA) is a straight chain macromolecular mucopolysaccharide composed Of repeat disaccharide units of glucuronic acid and N-acetylglucosamine. It widely consists in the extracellular space of human and animal tissue, vitreum, umbilical cord, skin joints synovia and cockscomb, etc. The commercial HA is commonly a sodium salt, called sodium hyaluronate, habitually called hyaluronic acid. HA is a new biological at home and abroad. Its molecular weight is from several ten thousand to several million. It's aqueous solution has outstanding moisture keeping ability, high viscoelasticity and lubricity. It is widely used in cosmetics, pharmacy and health and beauty food. 

Applications:

Biochemical drugs with high clinical value, which are widely used in all kinds of eye surgery, such as crystal implantation, corneal transplantation and glaucoma surgery, etc.Can also be used to treat arthritis and accelerate wound healing.Used in cosmetics, it can have unique skin protection effect, can keep skin moist and smooth, delicate, soft, elastic, has the anti-wrinkle, anti-wrinkle, beauty care and restore the skin physiology function.

1. Food Grade 
2. Cosmetic Grade 
3. Eyedrops Grade(Pharm Grade) 
4. Injection Grade(Pharm Grade) 
5. High molecular weight HA 
6. Low molecular weight HA

Product Name:Tetrahexyldecyl Ascorbate

Specification example:

CAS Number:638-94-8
Name:Desonide
Formula:C24H32O6
Molecular Weight:416.51
Synonyms:Prenacid;Desilux;Pregna-1,4-diene-3,20-dione,11,21- dihydroxy-16,17-[(1-methylethylidene)bis- (oxy)]-,(11a,16R)-;Topifug;Locapred;Tridesilon;Flusemidon;Hamiltoderm;Desonide [USAN:BAN:INN];Pregna-1,4-diene-3,20-dione, 11,21-dihydroxy-16,17-((1-methylethylidene)bis(oxy))-, (11beta,16alpha)-;Apolar;Otic Tridesilon;Steroderm;Prednisolone-16,17-acetonide, 16-alpha-hydroxy-;DesOwen;Tridesonit;Sterax;Desonidum [INN-Latin];Budesonide acetonide;
EINECS:211-351-6
Density:1.3 g/cm3
Boiling Point:580.1 °C at 760 mmHg
Flash Point:196.9 °C
Appearance:Powder

Application:

1. Can be absorbed through the skin antikeratinizing, stimulate the growth of collagen and elastin, increase the thickness of the epidermis and dermis. Enhance skin elasticity, eliminate wrinkles and promote skin renewal, keeping the skin vitality. For cream, moisturizing cream, Cream, shampoo, conditioner, etc.
2. Vitamin A acetate oil to maintain the body's normal metabolism, cell membrane to maintain stability and development, to maintain the normal function of the reproductive system, formation of the visual, ease keratinized tissue, enhance immunity cells have significant effects.

    Product Description

   Certification of Analysis

                          Function&Application

Cabazitaxel (previously XRP-6258) is a semi-synthetic derivative of a natural taxoid. It was developed by Sanofi-Aventis and was approved by the U.S. FDA for the treatment of hormone-refractory prostate cancer on June 17, 2010. It is a microtubule inhibitor, and the fourth taxane to be approved as a cancer therapy.

Cabazitaxel in combination with prednisone is a treatment option for hormone-refractory prostate cancer following docetaxel-based treatment.

 Cabazitaxel anticancer mechanism and characteristics similar with docetaxel, belongs to anti-microtubule drugs. Cabazitaxel through binding to tubulin, promoting their assembly into microtubules, and can prevent these have assembled a microtubule disintegration of the stabilization of microtubules, thereby inhibiting cell mitosis, and interphase cellular functions (interphasecellularfunctions) of play.