Sunitinib malate 341031-54-7
99% purity
<p> IUPAC Name: N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidine)methyl]-2,4-dimethyl-1Hpyrrole-3-carboxamide (2S)-2-hydroxybutanedioate salt.</p> <p> </p> <div> Description: </div> <div> Potent, ATP-competitive VEGFR, PDGFRβ KIT inhibitor</div> <div> (K values are 2, 9, 17, 8 4 nM fVEGFR -1, -2, -3, </div> <div> PDGFRβ KIT respectively). Also inhibits cellular receptor</div> <div> phosphorylation of FLT3, RET CSF-1R. Exhibits </div> <div> antiangiogenic antitumactivity in multiple xenograft </div> <div> models. </div> <div> Physical Chemical Properties: </div> <div> Batch Molecular Formula: C H FN O .C H O</div> <div> Batch Molecular Weight: 532.56 </div> <div> Physical Appearance:ange solid </div>
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